65144-03-8 Usage
Description
3-Hydroxystearic acid ethyl ester, also known as Ethyl 3-Hydroxyoctadecanoate, is a chemical compound derived from the esterification of 3-Hydroxystearic acid with ethanol. It is a colorless liquid with a slight odor and is soluble in organic solvents. 3-Hydroxystearic acid ethyl ester has a hydroxyl group attached to the 3rd carbon of the stearic acid chain, which provides unique chemical and physical properties.
Uses
Used in Pharmaceutical Industry:
3-Hydroxystearic acid ethyl ester is used as an intermediate in the synthesis of 3-Hydroxystearoylcarnitine Hydrochloride (H953630), a compound that has been found in overweight patients. This makes it a potential candidate for the development of drugs targeting weight management and obesity-related conditions.
Used in Chemical Synthesis:
3-Hydroxystearic acid ethyl ester can be used as a starting material for the synthesis of various other chemical compounds, such as surfactants, lubricants, and plasticizers. Its unique structure allows for the formation of esters, ethers, and other functional groups, making it a versatile building block in organic chemistry.
Used in Cosmetics and Personal Care Industry:
Due to its solubility and mild properties, 3-Hydroxystearic acid ethyl ester can be used as an ingredient in cosmetics and personal care products. It can act as an emollient, providing a smooth and soft texture to the skin, and can also be used as a solvent for other ingredients in formulations.
Used in Research and Development:
3-Hydroxystearic acid ethyl ester can be utilized in research and development for studying its properties and potential applications. It can be used to investigate the effects of hydroxyl groups on the physical and chemical properties of fatty acid esters, as well as to explore its potential use in various industries, such as pharmaceuticals, cosmetics, and chemical synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 65144-03-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,1,4 and 4 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 65144-03:
(7*6)+(6*5)+(5*1)+(4*4)+(3*4)+(2*0)+(1*3)=108
108 % 10 = 8
So 65144-03-8 is a valid CAS Registry Number.
65144-03-8Relevant articles and documents
Synthesis of Long-Chain β-Lactones and Their Antibacterial Activities against Pathogenic Mycobacteria
Santucci, Pierre,Dedaki, Christina,Athanasoulis, Alexandros,Gallorini, Laura,Munoz, Ana?s,Canaan, Stéphane,Cavalier, Jean-Fran?ois,Magrioti, Victoria
, p. 349 - 358 (2019/01/25)
In the quest for new antibacterial agents, a series of novel long- and medium-chain mono- and disubstituted β-lactones was developed. Their activity against three pathogenic mycobacteria—M. abscessus, M. marinum, and M. tuberculosis—was assessed by the resazurin microtiter assay (REMA). Among the 16 β-lactones synthesized, only 3-hexadecyloxetan-2-one (VM005) exhibited promising activity against M. abscessus, whereas most of the β-lactones showed interesting activities against M. marinum, similar to that of the classical antibiotic, isoniazid. Regarding M. tuberculosis, six compounds were found to be active against this mycobacterium, with β-lactone VM008 [trans-(Z)-3-(hexadec-7-en-1-yl)-4-propyloxetan-2-one] being the best growth inhibitor. The promising antibacterial activities of the best compounds in this series suggest that these molecules may serve as leads for the development of much more efficient antimycobacterial agents.
