651778-33-5

Basic information

• Product Name: 2,6-bis-(2,6-bis-benzoylamino-hexanoylamino)-hexanoic acid methyl ester
• Synonyms: 2,6-bis-(2,6-bis-benzoylamino-hexanoylamino)-hexanoic acid methyl ester
• CAS NO: 651778-33-5
• Molecular Weight: 832.997
• Mol File: 651778-33-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,6-bis-(2,6-bis-benzoylamino-hexanoylamino)-hexanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-bis-(2,6-bis-benzoylamino-hexanoylamino)-hexanoic acid methyl ester(651778-33-5)
• EPA Substance Registry System: 2,6-bis-(2,6-bis-benzoylamino-hexanoylamino)-hexanoic acid methyl ester(651778-33-5)

Safety Data

• Hazardous Substances Data: 651778-33-5(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 687-64-9 DL-lysine methyl ester 
• 32513-92-1 Nα,ε-dibenzoyl-D,L-lysine 

Relevant articles and documents

Syntheses of dendritic branches based on L-lysine: is the stereochemistry preserved throughout the synthesis?

This paper reports the syntheses of individual dendritic branches based on L-lysine and functionalised with either Boc or Bz surface groups. Convergent and divergent synthetic approaches were employed and the preservation of stereochemistry during the syntheses was monitored using polarmetry, NMR and HPLC. In addition, racemic dendritic branches based on D,L-lysine were synthesised for comparative purposes. It was observed that the preservation of stereochemistry in the dendritic peptide was dependent on the method of synthesis, with divergent methodology being preferred. The results are discussed in terms of the known stereochemical outcomes of traditional peptide coupling processes, and are generalised to the synthesis of other dendritic peptides. Such observations about the chirality of dendritic peptides are of relevance to chemists developing dendritic systems for applications where single enantiomer dendrimers would clearly be preferred, such as enantioselective catalysis or pharmaceutical chemistry.