652-24-4

Basic information

• Product Name: (pentafluorophenyl)glycolic acid
• Synonyms: (pentafluorophenyl)glycolic acid;α-Hydroxy-2,3,4,5,6-pentafluorobenzeneacetic acid;Einecs 211-486-0
• CAS NO: 652-24-4
• Molecular Formula: C₈H₃F₅O₃
• Molecular Weight: 242.099636
• EINECS: 211-486-0
• Mol File: 652-24-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 277.1°C at 760 mmHg
• Flash Point: 121.4°C
• Appearance: /
• Density: 1.777g/cm³
• Vapor Pressure: 0.00223mmHg at 25°C
• Refractive Index: 1.482
• CAS DataBase Reference: (pentafluorophenyl)glycolic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (pentafluorophenyl)glycolic acid(652-24-4)
• EPA Substance Registry System: (pentafluorophenyl)glycolic acid(652-24-4)

Safety Data

• Hazardous Substances Data: 652-24-4(Hazardous Substances Data)

Usage

Description

(pentafluorophenyl)glycolic acid is a chemical compound with the molecular formula C8H4F5O3, derived from glycolic acid and featuring a pentafluorophenyl group attached to the glycolic acid molecule. It is recognized for its applications in organic synthesis and its potential in the development of pharmaceutical, agrochemical products, and new materials with specific properties.

Uses

Used in Organic Synthesis:
(pentafluorophenyl)glycolic acid is used as a key intermediate for the synthesis of various pharmaceutical and agrochemical products, contributing to the development of new compounds with desired properties and applications.
Used in Material Science:
In the field of material science, (pentafluorophenyl)glycolic acid is utilized as a building block for the creation of new materials with specific characteristics, potentially enhancing their performance and expanding their range of applications.
Used in Pharmaceutical Research:
(pentafluorophenyl)glycolic acid is investigated for its potential biological and pharmacological activities, with ongoing research aimed at understanding its full potential in the development of new drugs and therapies.
Used in Agrochemical Development:
(pentafluorophenyl)glycolic acid is also explored for its applications in the agrochemical industry, where it may contribute to the development of novel products with improved efficacy and selectivity in crop protection and management.

InChI:InChI=1/C8H3F5O3/c9-2-1(7(14)8(15)16)3(10)5(12)6(13)4(2)11/h7,14H,(H,15,16)

Upstream product

• 653-37-2 perfluorobenzaldehyde 
• 151-50-8 potassium cyanide 
• 827-15-6 1,2,3,4,5-pentafluoro-6-iodobenzene 
• 344-04-7 bromopentafluorobenzene 
• 879-06-1 pentafluorophenylmagnesium chloride 
• 51978-44-0 ethyl pentafluorophenylglycolate 

Downstream Products

• 21514-53-4 2-Pentafluorphenyl-2-hydroxy-1-phenyl-ethanon 

Relevant articles and documents

Anti-viral compounds

The present invention relates to compounds of Formula (I) below, which inhibit the growth of picornaviruses, Hepatitus viruses, enteroviruses, cardioviruses, polioviruses, coxsackieviruses of the A and B groups, echo virus and Mengo virus. wherein: A is phenyl, pyridyl, substituted phenyl, substituted pyridyl, or benzyl; R is hydrogen, COR4, or COCF3; X is N—OH, O, or CHR1; R1is hydrogen, halo, CN, C1-C4alkyl, —C≡CH, CO(C1-C4alkyl), CO2(C1-C4alkyl), or CONR2R3; R2and R3are independently hydrogen or C1-C4alkyl; A′ is hydrogen, halo, C1-C6alkyl, benzyl, naphthyl, thienyl, furyl, pyridyl, pyrollyl, COR4, S(O)nR4, or a group of the formula R4is C1-C6alkyl, phenyl, or substituted phenyl; n is 0, 1, or 2; R5is independently at each occurrence hydrogen or halo; m is 1, 2, 3, or 4; and R6is hydrogen, halo, CF3, OH, CO2H, NH2, NO2, CONHOCH3, C1-C4alkyl, or CO2(C1-C4alkyl), C1-C4alkoxy; or a pharmaceutically acceptable salt thereof.