65246-99-3 Usage
Description
(2-amino-5-bromophenyl)(4-chlorophenyl)methanone is a complex organic chemical compound that features a 2-amino-5-bromophenyl group and a 4-chlorophenyl group connected to a methanone molecule. (2-amino-5-bromophenyl)(4-chlorophenyl)methanone is widely recognized for its utility in organic synthesis and medicinal chemistry, where it serves as a key building block for the creation of diverse pharmaceutical compounds and other organic substances. Its unique structural attributes and potential applications in drug development and chemical biology research make it a compound of significant interest. As with all chemicals, it is imperative to exercise proper handling and safety measures when working with (2-amino-5-bromophenyl)(4-chlorophenyl)methanone to mitigate any associated risks.
Uses
Used in Pharmaceutical Industry:
(2-amino-5-bromophenyl)(4-chlorophenyl)methanone is utilized as a crucial intermediate in the synthesis of various pharmaceutical compounds. Its unique molecular structure allows for the development of new drugs with potential therapeutic applications.
Used in Chemical Biology Research:
In the field of chemical biology, (2-amino-5-bromophenyl)(4-chlorophenyl)methanone is employed as a valuable tool for investigating the structure-function relationships of biologically relevant molecules. Its distinctive chemical properties facilitate a deeper understanding of molecular interactions and mechanisms.
Used in Organic Synthesis:
(2-amino-5-bromophenyl)(4-chlorophenyl)methanone is used as a versatile building block in organic synthesis, enabling the creation of a wide array of organic substances with diverse applications across various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 65246-99-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,2,4 and 6 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 65246-99:
(7*6)+(6*5)+(5*2)+(4*4)+(3*6)+(2*9)+(1*9)=143
143 % 10 = 3
So 65246-99-3 is a valid CAS Registry Number.
65246-99-3Relevant articles and documents
BROMODOMAIN TARGETING DEGRONIMERS FOR TARGET PROTEIN DEGRADATION
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Page/Page column 391, (2017/12/05)
This invention provides a Degronimer that has an E3 Ubiquitin Ligase targeting moiety (Degron) that can be linked to a Targeting Ligand for a bromodomain protein selected for in vivo degradation to achieve a therapeutic effect, and methods of use and compositions thereof as well as methods for their preparation.
DIHYDROQUINAZOLINONE ANALOGUES
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, (2014/10/16)
The present invention encompasses compounds of general formula (I) wherein the groups R1 to R4 and A1 to A5 have the meanings given in the claims and in the specification. The compounds of the invention are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation pharmaceutical preparations containing such compounds and their uses as a medicament.
New vistas in quinoline synthesis
Atechian, Sarkis,Nock, Nadine,Norcross, Roger D.,Ratni, Hassen,Thomas, Andrew W.,Verron, Julien,Masciadri, Raffaello
, p. 2811 - 2823 (2007/10/03)
The gold-catalyzed Friedlander reaction was applied to the condensation of 2-aminoarylketones with β-keto-esters, β-diketones, β-keto-amides, and β-keto-sulfones to afford a diverse range of 2,3,4-trisubstituted quinolines in 3-82% yield. The seven-membered rings 1,3-cycloheptadione and azepane-2,4-dione reacted smoothly in 75% yield. An alternative procedure for the synthesis of 3-(methanesulfonyl)quinolines was developed and provided an entry into late stage manipulation of the 4-position of these quinolines. The requisite 2-aminoarylketones for the Friedlander reaction were prepared in one pot by modified Sugasawa reaction using gallium(III) chloride and boron(III) chloride in 12-54% yield.
