65332-45-8

Basic information

• Product Name: Demethylvestitol
• Synonyms: 4-(3,4-Dihydro-7-hydroxy-2H-1-benzopyran-3-yl)-1,3-benzenediol;Demethylvestitol;2',4',7-Trihydroxyisoflavan
• CAS NO: 65332-45-8
• Molecular Formula: C₁₅H₁₄O₄
• Molecular Weight: 258.27
• Mol File: 65332-45-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 490.9±34.0 °C(Predicted)
• Appearance: /
• Density: 1.382±0.06 g/cm3(Predicted)
• PKA: 9.69±0.40(Predicted)
• CAS DataBase Reference: Demethylvestitol(CAS DataBase Reference)
• NIST Chemistry Reference: Demethylvestitol(65332-45-8)
• EPA Substance Registry System: Demethylvestitol(65332-45-8)

Safety Data

• Hazardous Substances Data: 65332-45-8(Hazardous Substances Data)

Usage

Description

Demethylvestitol is a naturally occurring isoflavonoid compound found in certain plants, particularly within the Baptisia genus. It is a derivative of the well-known isoflavone vestitol and has garnered interest due to its potential medicinal properties. These include its ability to inhibit the growth of cancer cells, its anti-inflammatory effects, and its estrogen-like activity, which has shown promise as a potential treatment for osteoporosis. With its unique chemical structure and biological activities, demethylvestitol is an intriguing compound for future studies in drug development and natural medicine.

Uses

Used in Pharmaceutical Industry:
Demethylvestitol is used as an anticancer agent for its potential to inhibit the growth of cancer cells. Its unique chemical structure allows it to target and interfere with the mechanisms that drive cancer progression, making it a promising candidate for further research and development in oncology.
Used in Anti-Inflammatory Applications:
Demethylvestitol is used as an anti-inflammatory agent due to its ability to reduce inflammation. This property can be beneficial in treating various inflammatory conditions and may contribute to its potential use in managing chronic inflammatory diseases.
Used in Osteoporosis Treatment:
Demethylvestitol is used as a potential treatment for osteoporosis because of its estrogen-like activity. This characteristic suggests that it may help in maintaining bone density and strength, thus providing a natural alternative for managing and treating osteoporosis.
Further research is necessary to fully understand the potential benefits and risks associated with the use of demethylvestitol, but its diverse applications across different medical fields highlight its significance in the realm of natural medicine and drug development.

Upstream product

• 7678-85-5 2',4',7-trihydroxyisoflavone 
• 62027-17-2 2',4',7-tribenzyloxyisoflavone 
• 141330-22-5 (+/-)-3-<2,4-Bis(methoxymethoxy)phenyl>-3,4-dihydro-7-(methoxymethoxy)-2H-1-benzopyran 
• 141330-20-3 7-(Methoxymethoxy)-3-<4-(methoxymethoxy)phenyl>-4H-1-benzopyran-4-on 
• 113250-45-6 3-<2,4-Bis(methoxymethoxy)phenyl>-7-(methoxymethoxy)-4H-1-benzopyran-4-on 
• 141330-31-6 (+/-)-3-<2,4-Bis(methoxymethoxy)phenyl>-2,3-dihydro-7-(methoxymethoxy)-4H-1-benzopyran-4-on 
• 141330-21-4 3-<2,4-Bis<(2-methoxyethoxy)methoxy>phenyl>-7-<(2-methoxyethoxy)methoxy>-4H-1-benzopyran-4-on 
• 141330-26-9 (+/-)-trans-3-<2,4-Bis(methoxymethoxy)phenyl>-3,4-dihydro-7-(methoxymethoxy)-2H-1-benzopyran-4-ol 
• 141330-26-9 (+/-)-cis-3-<2,4-Bis(methoxymethoxy)phenyl>-3,4-dihydro-7-(methoxymethoxy)-2H-1-benzopyran-4-ol 

Relevant articles and documents

Synthesis and behaviour of isoflavones substituted in 2'-position

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PHASEOLLIN FORMATION AND METABOLISM IN PHASEOLUS VULGARIS

Following fungal-inoculation, P. vulgaris was found to produce small amounts of 7,4'-dihydroxyisoflavone (daidzein), 7,2',4'-trihydroxyisoflavone, 7,2',4'-trihydroxyisoflavanone, (6aR,11aR)-3,9-dihydroxypterocarpan, and (3R)-5,2',4'-trihydroxyisoflavan.Th