65358-01-2Relevant articles and documents
Diels-Alder Reactions of 7-Azalumazines. Synthesis of Condensed Lumazines and 8-Deazalumazines
Taylor, Edward C.,Pont, Joseph L.,Warner, John C.
, p. 3568 - 3572 (2007/10/02)
7-Azalumazines tethered at the C6 position with a series of dienophilic side chains undergo intramolecular Diels-Alder reactions to provide 6,7-annulated lumazines and 8-deazalumazines.The rates of these cycloaddition reactions are markedly faster than for previously reported cycloadditions of isomeric C7-tethered 6-azalumazines.On the other hand, 7-azalumazines do not undergo intermolecular Diels-Alder reactions with enamine dienophiles, whereas under identical conditions, 6-azalumazines react readily.Reasons for this striking reversal in reactivity observed for inter- and intramolecular Diels-Alder reactions of 6- vs 7-azalumazines are discussed.
N-Bromosuccinimide in Heterocyclic Synthesis. Synthesis of Pyrazolopyrimidines, Pyrimido-as-triazines, and Pyrimidopyridazines from 6-Arylidenehydrazino-1,3-dimethyluracil Derivatives
Kanazawa, Hashime,Nishigaki, Sadao,Senga, Keitaro
, p. 969 - 974 (2007/10/02)
Reactions of 6-arylidenehydrazino-1,3-dimethyluracil derivatives with N-bromosuccinimide leading to pyrazolopyrimidines, pyrimido-as-triazines, and pyrimidopyridazines are described.