653580-54-2

Basic information

• Product Name: Benzenepropanoyl chloride, 4-methoxy-3-(phenylmethoxy)-
• CAS NO: 653580-54-2
• Molecular Formula: C17H17ClO3
• Molecular Weight: 304.773
• Mol File: 653580-54-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenepropanoyl chloride, 4-methoxy-3-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoyl chloride, 4-methoxy-3-(phenylmethoxy)-(653580-54-2)
• EPA Substance Registry System: Benzenepropanoyl chloride, 4-methoxy-3-(phenylmethoxy)-(653580-54-2)

Safety Data

• Hazardous Substances Data: 653580-54-2(Hazardous Substances Data)

Upstream product

• 159749-96-9 <3-(Benzyloxy)-4-methoxyphenyl>propionic acid benzyl ester 
• 1135-15-5 dihydroisoferulic acid 
• 537-73-5 isoferulic acid 
• 36418-96-9 3-<3-(Benzyloxy)-4-methoxyphenyl>propionic acid 

Downstream Products

• 653579-84-1 4-(3-benzyloxy-4-methoxyphenyl)-1-diazo-butan-2-one 
• 74904-31-7 5-benzyl-3,4-dihydro-6-hydroxy-7-methoxyisocarbostyril 
• 855269-31-7 2-Benzyloxy-4-(2-isocyanato-ethyl)-1-methoxy-benzene 
• 127399-74-0 1,2,3,4-tetrahydro-6-(benzyloxy)-7-methoxy-2(1H)-naphthalenone 
• 872783-60-3 3-(3-Benzyloxy-4-methoxy-phenyl)-propionyl azide 

Relevant articles and documents

8,9-Methylenedioxybenzo[i]phenanthridines: Topoisomerase I-targeting activity and cytotoxicity

Substituted benzo[i]phenanthridines that have incorporated within their structure an 8,9-methylenedioxy group can exhibit topoisomerase I-targeting activity. Structure-activity studies were performed to examine the influence of saturation at the 11,12-positions of several substituted 8,9-methylenedioxybenzo[i]phenanthridines. The activities of these dihydro analogues were compared to those of their unsaturated analogues. In addition, the influence of varying substituents at the 2- and 3-positions within the A-ring of these 8,9-methylenedioxybenzo[i]phenanthridines on their relative potency as topoisomerase I-targeting agents and cell proliferation as determined using the MTT assay was investigated. 2,3-Dimethoxy-8,9-methylenedioxybenzo[i]phenanthridine and its 11,12-dihydro derivative were among the more potent analogues evaluated with regard to topoisomerase I-targeting activity and cytotoxicity.