654-49-9 Usage
General Description
6-Methyl-2-oxo-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile is a chemical compound with the molecular formula C8H6F3N3O. It is a yellow solid with a molecular weight of 207.15 g/mol. 6-METHYL-2-OXO-4-(TRIFLUOROMETHYL)-1,2-DIHYDROPYRIDINE-3-CARBONITRILE is commonly used in organic synthesis and pharmaceutical research due to its potential biological activities. Specifically, it has been studied for its potential as a cardiovascular drug and as an inhibitor of tyrosinase, an enzyme involved in the production of melanin. Its unique chemical structure makes it a useful building block for the synthesis of more complex molecules and pharmaceuticals. However, it is important to handle this compound with care, as it may have hazardous properties and should only be used by trained professionals in a controlled laboratory environment.
Check Digit Verification of cas no
The CAS Registry Mumber 654-49-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,5 and 4 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 654-49:
(5*6)+(4*5)+(3*4)+(2*4)+(1*9)=79
79 % 10 = 9
So 654-49-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H5F3N2O/c1-4-2-6(8(9,10)11)5(3-12)7(14)13-4/h2H,1H3,(H,13,14)
654-49-9Relevant articles and documents
A simple and facile method for the synthesis of novel 5/7 triflouromethyl-substituted 4(3H)-quinazolone regioisomers
Maitraie,Venkat Reddy,Rama Rao,Ravi Kanth,Shanthan Rao,Narsaiah
, p. 73 - 79 (2007/10/03)
The unsymmetrical 1,3-diketones 1 on reaction with malononitrile is resulted an interesting trifunctional intermediates 2 and 3. The intermediate 2 is hydrolyzed to give 2,6-dicarboxamido aniline 4 which on cyclisation gave two regioisomers of 1,2-dihydro-4(3H)-quinazolinones 5 and 6. The effect of substituents on compound 4 is characteristic for formation of regioisomers in different proportions. Each regioisomer on dehydrogenation under mild condition using active MnO2 gave corresponding 4(3H)-quinazolones 7 and 8, respectively.
