654055-80-8

Basic information

• Product Name: Ethanone, 1-[(3R,4S,5S,6R)-6-hydroxy-5-methoxy-1-oxaspiro[2.5]oct-4-yl]-, O-(phenylmethyl)oxime, (1E)-
• CAS NO: 654055-80-8
• Molecular Formula: C17H23NO4
• Molecular Weight: 305.374
• Mol File: 654055-80-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[(3R,4S,5S,6R)-6-hydroxy-5-methoxy-1-oxaspiro[2.5]oct-4-yl]-, O-(phenylmethyl)oxime, (1E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[(3R,4S,5S,6R)-6-hydroxy-5-methoxy-1-oxaspiro[2.5]oct-4-yl]-, O-(phenylmethyl)oxime, (1E)-(654055-80-8)
• EPA Substance Registry System: Ethanone, 1-[(3R,4S,5S,6R)-6-hydroxy-5-methoxy-1-oxaspiro[2.5]oct-4-yl]-, O-(phenylmethyl)oxime, (1E)-(654055-80-8)

Safety Data

• Hazardous Substances Data: 654055-80-8(Hazardous Substances Data)

Upstream product

• 654055-67-1 acetic acid 4-chloromethyl-4-hydroxy-2-methoxy-3-[2-methyl-3-(3-methylbut-2-enyl)oxiranyl]cyclohexyl ester 
• 654055-69-3 acetic acid 4-(1,5-dimethylhexa-1,4-dienyl)-5-methoxy-1-oxaspiro[2.5]oct-6-yl ester 
• 669064-70-4 Acetic acid (3R,4S,5S,6R)-4-acetyl-5-methoxy-1-oxa-spiro[2.5]oct-6-yl ester 
• 35903-52-7 fumagillol 
• 622-33-3 N-benzyloxyamine 
• 669064-72-6 Acetic acid (3R,4S,5S,6R)-4-{1-[(E)-benzyloxyimino]-ethyl}-5-methoxy-1-oxa-spiro[2.5]oct-6-yl ester 

Downstream Products

• 654055-75-1 carbonic acid 4-(1-benzyloxyiminoethyl)-5-methoxy-1-oxaspiro[2.5]oct-6-yl ester 4-nitrophenyl ester 

Relevant articles and documents

Investigation of novel fumagillin analogues as angiogenesis inhibitors

Modification of fumagillin was conducted to develop MetAP-2 inhibitors with desirable pharmacological properties. Replacement of the C4 side chain by benzyloxime preserves the inhibitory activity against MetAP-2 enzyme. Fumagillin analogues containing the