65429-74-5

Basic information

• Product Name: 3-Pyridinecarbonitrile, 1,2-dihydro-4-(4-methylphenyl)-2-oxo-6-phenyl-
• CAS NO: 65429-74-5
• Molecular Formula: C19H14N2O
• Molecular Weight: 286.333
• Mol File: 65429-74-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarbonitrile, 1,2-dihydro-4-(4-methylphenyl)-2-oxo-6-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarbonitrile, 1,2-dihydro-4-(4-methylphenyl)-2-oxo-6-phenyl-(65429-74-5)
• EPA Substance Registry System: 3-Pyridinecarbonitrile, 1,2-dihydro-4-(4-methylphenyl)-2-oxo-6-phenyl-(65429-74-5)

Safety Data

• Hazardous Substances Data: 65429-74-5(Hazardous Substances Data)

Upstream product

• 77609-07-5 2-(1-(4-methylphenyl)-3-oxo-3-phenylpropyl)malononitrile 
• 104-87-0 4-methyl-benzaldehyde 
• 52287-59-9 (E)-2-cyano-3-(4-methylphenyl)acrylamide 
• 98-86-2 acetophenone 
• 18300-87-3 ethyl 2-cyano-3-p-tolylacrylate 
• 4224-87-7 4-methyl-chalcone 
• 107-91-5 cyanoacetic acid amide 
• 19310-59-9 2-cyano-3-(p-tolyl)acrylamide 
• 76983-09-0 2-Oxo-6-phenyl-4-p-tolyl-1,2,3,4-tetrahydro-pyridine-3-carbonitrile 
• 25855-99-6 1-(4-methylphenyl)-3-phenyl-1,3-propanedione 

Downstream Products

• 548487-51-0 6-phenyl-4-p-tolyl-pyridin-2-ol 
• 143882-76-2 2-chloro-4-(4-methylphenyl)-6-phenyl-pyridine-3-carbonitrile 
• 74873-35-1 2-amino-4-(4-methyl-phenyl)-6-phenyl-pyridine-3-carbonitrile 
• 156638-73-2 2-azido-4-(4-methyl-phenyl)-6-phenyl-pyridine-3-carbonitrile 
• 156638-76-5 4-(4-methyl-phenyl)-6-phenyl-2-(triphenylphosphoranylideneamino)-pyridine-3-carbonitrile 

Relevant articles and documents

One-Pot Sequential Synthesis of Fused Isoquinolines via Intramolecular Cyclization/Annulation and their Photophysical Investigation

One of the cyano group of γ-keto malononitrile gets hydrolyzed selectively to an amide in the presence of copper(II) acetate monohydrate. The in situ generated amide undergo an intramolecular dehydrative cyclization to a 1,2-dihydropyridone intermediate.

A microwave approach to the synthesis of certain 4-(substituted phenyl)-6-phenyl-3-cyano-2-pyridones

A study of the synthesis of 4-(substituted phenyl)-6-phenyl-3-cyano- 2-pyridones from ethyl 2-cyano-3-(substituted phenyl) acrylates and acetophenone is presented. The 2-pyridones were obtained using conventional as well as microwave synthesis under solvent and solvent-free conditions in domestic and laboratory microwave ovens. The structure of the obtained pyridones was confirmed by m.p., FT-IR, NMR and UV data.

Synthesis of aminopyridines from azidopyridines and tetrazolo[1,5-a]pyridines

3-Cyano-1,2-dihydro-pyridine-2-ones 2 have been synthesized via the base-catalyzed cycloaddition of arylidenecyanoacetamide 1 with acetophenone. Chlorination of 2 with POCl3/PCl5 mixture gave the corresponding chloropyridines 3. Reac