65490-24-6 Usage
Description
Anhydrochlortetracycline hydrochloride, which can be used as a secondary standard, is an anhydro analogue and impurity of Chlortetracycline. It is an antimicrobial and antibacterial agent that can be utilized for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
Anhydrochlortetracycline hydrochloride, which can be used as a secondary standard, is used as an antimicrobial agent for treating bacterial infections. Its antibacterial properties make it effective against a wide range of bacteria, contributing to its use in the development of antibiotics and other pharmaceutical products.
Used in Research and Quality Control:
Anhydrochlortetracycline hydrochloride, which can be used as a secondary standard, is used as a reference material in research and quality control processes. Its well-defined purity and properties allow it to serve as a reliable standard for the accurate measurement and analysis of other substances in various applications.
Used in Environmental and Industrial Applications:
Anhydrochlortetracycline hydrochloride, which can be used as a secondary standard, is also utilized in environmental and industrial applications. Its antimicrobial properties can be employed to control bacterial growth in various settings, such as water treatment, agriculture, and industrial processes, ensuring cleanliness and safety.
Check Digit Verification of cas no
The CAS Registry Mumber 65490-24-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,4,9 and 0 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 65490-24:
(7*6)+(6*5)+(5*4)+(4*9)+(3*0)+(2*2)+(1*4)=136
136 % 10 = 6
So 65490-24-6 is a valid CAS Registry Number.
65490-24-6Relevant articles and documents
Semisynthetic analogues of anhydrotetracycline as inhibitors of tetracycline destructase enzymes
Markley, Jana L.,Fang, Luting,Gasparrini, Andrew J.,Symister, Chanez T.,Kumar, Hirdesh,Tolia, Niraj H.,Dantas, Gautam,Wencewicz, Timothy A.
, p. 618 - 633 (2019/03/19)
The synthesis and biological evaluation of semisynthetic anhydrotetracycline analogues as small molecule inhibitors of tetracycline-inactivating enzymes are reported. Inhibitor potency was found to vary as a function of enzyme (major) and substrate-inhibitor pair (minor), and anhydrotetracycline analogue stability to enzymatic and nonenzymatic degradation in solution contributes to their ability to rescue tetracycline activity in whole cell Escherichia coli expressing tetracycline destructase enzymes. Taken collectively, these results provide the framework for the rational design of next-generation inhibitor libraries en route to a viable and proactive adjuvant approach to combat the enzymatic degradation of tetracycline antibiotics.
