65518-20-9

Basic information

• Product Name: DL-Canaline dihydrochloride
• Synonyms: DL-Canaline dihydrochloride;DL-Canaline 2HCl;O-AMINO-DL-HOMOSERINE DIHYDROCHLORIDE;2-amino-4-(aminooxy)butanoic acid dihydrochloride;REF DUPL: DL-Canaline dihydrochloride;DL-Canaline 2HCl DL-Canaline dihydrochloride
• CAS NO: 65518-20-9
• Molecular Formula: C4H12Cl2N2O3
• Molecular Weight: 207.06
• Mol File: 65518-20-9.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 402.1 °C at 760 mmHg
• Flash Point: 197 °C
• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: DL-Canaline dihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: DL-Canaline dihydrochloride(65518-20-9)
• EPA Substance Registry System: DL-Canaline dihydrochloride(65518-20-9)

Safety Data

• Hazardous Substances Data: 65518-20-9(Hazardous Substances Data)

Usage

General Description

DL-Canaline dihydrochloride is a synthetic analog of L-canavanine, a non-protein amino acid found in certain legumes. It is a potent and irreversible inhibitor of ornithine decarboxylase, an enzyme involved in the biosynthesis of polyamines. Polyamines play crucial roles in cell growth, proliferation, and differentiation, and their dysregulation has been implicated in various diseases, including cancer. DL-Canaline dihydrochloride has been shown to inhibit cell growth and induce apoptosis in cancer cell lines, making it a promising candidate for the development of new anticancer therapies. Additionally, it has also been investigated for its potential to modulate immune responses and as a tool in the study of polyamine metabolism.