65519-49-5

Basic information

• Product Name: cyclo(L-Leu-L-Ser (Tos))
• CAS NO: 65519-49-5
• Molecular Weight: 354.427
• Mol File: 65519-49-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: cyclo(L-Leu-L-Ser (Tos))(CAS DataBase Reference)
• NIST Chemistry Reference: cyclo(L-Leu-L-Ser (Tos))(65519-49-5)
• EPA Substance Registry System: cyclo(L-Leu-L-Ser (Tos))(65519-49-5)

Safety Data

• Hazardous Substances Data: 65519-49-5(Hazardous Substances Data)

Upstream product

• 85328-90-1 (S)-2-((S)-2-tert-butoxycarbonylamino-3-hydroxypropanoylamino)-4-methylpentanoic acid methyl ester 
• 2666-93-5 (S)-Leu-OMe 

Relevant articles and documents

Cyclo(dehydroala-L-Leu), an α-glucosidase inhibitor from Penicillium sp. F70614

A diketopiperazine (1) has been isolated from the culture broth of Penicillium sp. F70614 and its structure has been determined to be cyclo(dehydroala-L-Leu) by various spectroscopic analyses. This compound selectively inhibited yeast α-glucosidase and porcine intestinal α-glucosidase with IC50 values of 35 and 50 μg/ml, respectively. However, it did not show significant inhibitory effects against almond β-glucosidase, Aspergillus α-galactosidase, Escherichia coli β-galactosidase and jack bean α-mannosidase.