6552-45-0

Basic information

• Product Name: alpha-cyclopropyl-4-methoxybenzyl alcohol
• Synonyms: alpha-cyclopropyl-4-methoxybenzyl alcohol;α-Cyclopropyl-4-methoxybenzenemethanol;cyclopropyl-(4-methoxyphenyl)methanol
• CAS NO: 6552-45-0
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.22766
• EINECS: 229-472-8
• Mol File: 6552-45-0.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: alpha-cyclopropyl-4-methoxybenzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: alpha-cyclopropyl-4-methoxybenzyl alcohol(6552-45-0)
• EPA Substance Registry System: alpha-cyclopropyl-4-methoxybenzyl alcohol(6552-45-0)

Safety Data

• Hazardous Substances Data: 6552-45-0(Hazardous Substances Data)

Upstream product

• 4333-56-6 cyclopropyl bromide 
• 123-11-5 4-methoxy-benzaldehyde 
• 7152-03-6 p-methoxyphenyl cyclopropyl ketone 
• 20525-76-2 dicyclopropylzinc 
• 23719-80-4 cyclopropylmagnesium bromide 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 1489-69-6 Cyclopropanecarboxaldehyde 

Downstream Products

• 183200-34-2 (E)-1-(4-bromobut-1-en-1-yl)-4-methoxybenzene 
• 7152-03-6 p-methoxyphenyl cyclopropyl ketone 
• 1108697-85-3 N-[cyclopropyl(4-methoxyphenyl)methyl]-4-methylbenzenesulfonamide 
• 1608462-21-0 1-(1-cyclopropylbut-3-enyl)-4-methoxybenzene 
• 16510-27-3 1-(cyclopropylmethyl)-4-methoxybenzene 
• 92587-78-5 trans-4-(p-methoxyphenyl)-3-buten-1-ol 
• 339079-71-9 (E/Z)-4-(4-methoxyphenyl)but-3-en-1-ol 

Relevant articles and documents

CuBr2-catalyzed ring opening/formylation reaction of cyclopropyl carbinols with DMF to synthesize formate esters

An unprecedented protocol for the synthesis of formate esters has been developed by employing N,N-dimethylformamide (DMF) as both the source of CHO and solvent. This reaction undergoes ring opening of the cyclopropyl carbinols and in situ formation of homoallylic alcohols, which reacts with DMF to give the desired products. The substrate cyclopropyl carbinols with different groups participate smoothly in this process and the desired products are obtained in moderate to good yields.

A method for synthesis of homoallylic bromide

Cyclopropyl Grignard reagents react with carbonyl compounds in the presence of diethyl phosphite to give homoallylic bromides. The reaction is effectively carried out under mild conditions in a one-pot fashion with moderate to good yields.

A catalytic and enantioselective cyclopropylation of aldehydes using dicyclopropylzinc

Enantioselective cyclopropylation of various aldehydes proceeds using dicyclopropylzinc in the presence of a catalytic amount of chiral amino alcohol or thiophosphoramidate with Ti(OPr1)4 to provide enantiomerically enriched cyclopropyl alkanols (up to 96.6% ee).