655256-68-1

Basic information

• Product Name: 1-[2-(4-Methylpiperazin-1-yl)phenyl]methanamine
• Synonyms: 2-(4-Methylpiperazin-1-yl)benzylamine 97%;[2-(4-Methylpiperazin-1-yl)phenyl]methylamine 97%;2-(4-Methylpiperazin-1-yl)benzylamine, 1-[2-(Aminomethyl)]phenyl]-4-methylpiperazine;[2-(4-Methylpiperazin-1-yl)phenyl]methylamine;1-[2-(4-Methylpiperazin-1-yl)phenyl]methamine;ART-CHEM-BB B021975;AKOS B021975;2-(4-METHYLPIPERAZINO)BENZYLAMINE
• CAS NO: 655256-68-1
• Molecular Formula: C₁₂H₁₉N₃
• Molecular Weight: 205.3
• EINECS: 1312995-182-4
• Product Categories: Amines and Anilines;Heterocycles;Piperaizine;Piperazidine intermediates;Piperazines
• Mol File: 655256-68-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 337.6 °C at 760 mmHg
• Flash Point: 155.7 °C
• Appearance: /
• Density: 1.065 g/cm³
• Vapor Pressure: 0.000104mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: 1-[2-(4-Methylpiperazin-1-yl)phenyl]methanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-(4-Methylpiperazin-1-yl)phenyl]methanamine(655256-68-1)
• EPA Substance Registry System: 1-[2-(4-Methylpiperazin-1-yl)phenyl]methanamine(655256-68-1)

Safety Data

• Hazard Codes: C
• Statements: 21/22-34
• Safety Statements: 23-26-36/37/39-45
• HazardClass: IRRITANT
• Hazardous Substances Data: 655256-68-1(Hazardous Substances Data)

Usage

General Description

1-[2-(4-Methylpiperazin-1-yl)phenyl]methanamine is a chemical compound with the molecular formula C13H20N2. It is a member of the phenylmethanamine class of organic compounds and contains a piperazine moiety as a part of its structure. 1-[2-(4-Methylpiperazin-1-yl)phenyl]methanamine is often used as a reagent in chemical reactions and synthetic processes, and it may also have pharmaceutical applications due to its structural similarity to other biologically active compounds. Additionally, its unique structural features make it a potential candidate for further research and development in medicinal chemistry and drug discovery. Overall, 1-[2-(4-Methylpiperazin-1-yl)phenyl]methanamine is a versatile chemical with potential uses in various fields, including organic synthesis and pharmaceuticals.

InChI:InChI=1/C12H19N3/c1-14-6-8-15(9-7-14)12-5-3-2-4-11(12)10-13/h2-5H,6-10,13H2,1H3

Upstream product

• 85803-63-0 2-(4-methylpiperazin-1-yl)benzonitrile 
• 85803-62-9 2-(4-methylpiperazin-1-yl)benzaldehyde 

Downstream Products

• 1028336-89-1 4-chloro-6-[2-(4-methyl-piperazin-1-yl)-benzylamino]-2H-phthalazin-1-one 
• 1426530-72-4 7-bromo-N-(2-methyl-5-(2-(4-methylpiperazin-1-yl)benzylcarbamoyl)phenyl)imidazo[1,2-a]pyridine-3-carboxamide 
• 1426531-74-9 3-amino-4-methyl-N-(2-(4-methylpiperazin-1-yl)benzyl)benzamide 
• 1426531-72-7 5-amino-2-fluoro-4-methyl-N-(2-(4-methylpiperazin-1-yl )benzyl)benzamide 
• 1426530-69-9 7-bromo-N-(2-fluoro-5-(2-(4-methylpiperazin-1-yl)benzylcarbamoyl)phenyl)imidazo[1,2-a]pyridine-3-carboxamide 
• 1426531-15-8 3-amino-4-bromo-N-(2-(4-methylpiperazin-1-yl)benzyl)benzamide 
• 1426531-14-7 N-(2-bromo-5-(2-(4-methylpiperazin-1-yl)benzylcarbamoyl)phenyl)imidazo[1,2-a]pyridine-3-carboxamide 
• 1426530-96-2 6-(1-methyl-1H-pyrazol-5-yl)-N-(2-methyl-5-((2-(4-methylpiperazin-1-yl)benzyl)carbamoyl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carboxamide 
• 1426531-12-5 6-bromo-N-(2-methyl-5-(2-(4-methylpiperazin-1-yl)benzylcarbamoyl)phenyl)pyrazolo[1,5-a]pyridine-3-carboxamide 

Relevant articles and documents

PIPERAZINYLPHENALKYL LACTAM/AMINE LIGANDS FOR THE 5HT1B RECEPTOR

The present invention relates to novel derivatives, that are compounds of Formula (I), wherein R1, R2, R3, R14, X, Y, n and m are defined herein, their pharmaceutically acceptable salts, pharmaceutical compositions and methods using said compounds in treating or preventing depression, anxiety, obsessive compulsive disorder (OCD) and other disorders for which selective antagonists, inverse agonists and partial agonists of serotonin 1 (5-HT1) receptors, specifically, antagonists of 5-HT1B are useful.