65535-84-4Relevant articles and documents
The direct conversion of carbamates to ureas using aluminum amides
Lee, Sang-Hyuep,Matsushita, Hana,Clapham, Bruce,Janda, Kim D.
, p. 3439 - 3443 (2004)
The conversion of carbamates into ureas using aluminum amide complexes is reported. This reaction is a convenient method to prepare bi-, tri- and tetra-substituted ureas from carbamate-protected primary or secondary amines by reaction with primary or secondary amines in the presence of stoichometric quantities of trimethylaluminum. A reactivity trend of the various carbamates was observed and methyl and benzyl carbamates were reacted selectively in the presence of t-butyl carbamates.
