6554-21-8Relevant articles and documents
MONOMER FOR SYNTHESIS OF RNA, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING RNA
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Paragraph 0137, (2015/06/16)
The objective of the present invention is to provide a monomer for RNA synthesis which can be efficiently produced and therefore by which the producing cost of RNA can be remarkably decreased, and a method for efficiently producing the monomer in a small number of steps. In addition, the objective of the present invention is also to provide a method by which RNA can be efficiently produced even when a approximately stoichiometry amount of the monomer for RNA synthesis is used. The monomer for RNA synthesis according to the present invention is represented by the following formula (I) or (I'): wherein R1 is a protective group of the hydroxy group and R2 is an alkyl group or the like.
The action of adenosine deaminase (E.C. 3.5.4.4.) on adenosine and deoxyadenosine acetates: The crucial role of the 5'-hydroxy group for the enzyme activity
Ciuffreda, Pierangela,Casati, Silvana,Santaniello, Enzo
, p. 3239 - 3243 (2007/10/03)
From adenosine 1, 2'-deoxyadenosine 3 and 3'-deoxyadenosine 5 all the acetates were prepared by lipase-catalyzed reactions. Only the acetates with free 5'-hydroxy group were deaminated by adenosine deaminase (ADA), confirming the crucial role of 5'-OH for the enzyme activity. (C) 2000 Elsevier Science Ltd.
A specific colorimetric and cytochemical substrate for ribonuclease T 2 : adenosine-3'-( -naphtylphosphate).
Kole,Sierakowska,Shugar
, p. 323 - 330 (2007/10/07)
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