65548-47-2

Basic information

• Product Name: 2H-1-Benzopyran, 7-methoxy-2-phenyl-
• CAS NO: 65548-47-2
• Molecular Formula: C16H14O2
• Molecular Weight: 238.286
• Mol File: 65548-47-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2H-1-Benzopyran, 7-methoxy-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran, 7-methoxy-2-phenyl-(65548-47-2)
• EPA Substance Registry System: 2H-1-Benzopyran, 7-methoxy-2-phenyl-(65548-47-2)

Safety Data

• Hazardous Substances Data: 65548-47-2(Hazardous Substances Data)

Upstream product

• 673-22-3 2-Hydroxy-4-methoxybenzaldehyde 
• 4363-35-3 Dihydroxy-styryl-boran 
• 588-72-7 [(E)-2-bromoethenyl]benzene 
• 678554-43-3 C₁₅H₁₆N₂O₄S 
• 1255508-81-6 2-ethoxy-7-methoxy-2H-chromene 
• 98-80-6 phenylboronic acid 
• 52923-29-2 1-(2-hydroxy-4-methoxyphenyl)-3-phenylprop-2-en-1-one 
• 552-41-0 1-(2-hydroxy-4-methoxyphenyl)ethanone 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 21785-09-1 7-methoxyflavanone 

Relevant articles and documents

Glycerol as an efficient medium for the Petasis borono-mannich reaction

The multicomponent Petasis borono-Mannich (PBM) reaction is a useful tool for the preparation of complex molecules in a single step from boronic acids, aldehydes/ketones, and amines. Here, we describe the use of glycerol in the PBM reaction of salicylalde

Rhodium-catalyzed cyclopropanations of 2-aryl-2H-chromenes with dialkyl malonate esters. A comparison of α-diazo derivatives and phenyliodonium ylides

Rhodium-catalyzed reactions of 2-aryl-substituted 2H-chromenes with α-diazo esters prepared from dimethyl and tert-butyl methyl malonates were investigated, and the results were compared with reactions carried out with phenyliodonium ylides prepared from the same esters. The phenyliodonium ylide prepared from dimethyl malonate was found to give superior yields of cyclopropane products compared to the corresponding α-diazo equivalent. However, this result was reversed with tert-butyl methyl malonate when Rh 2(S-TBSP)4 was used to decompose the diazo compound. All reactions gave 1,1-cyclopropane diesters as single diastereomers.

Synthesis and antimalarial evaluation of novel benzopyrano[4,3-b]benzopyran derivatives

7-Methoxyflavenes and 5,7,8-trimethoxyflavenes were found to undergo stereoselective acid-catalyzed rearrangement to generate the benzopyrano[4,3-b]benzopyran ring system present in the natural product, dependensin. Dependensin and its analogs were subjected to antimalarial growth inhibition assays against Plasmodium falciparum and found to have IC 50 values ranging between 1.9 and 3.9 μM.