65562-25-6

Basic information

• Product Name: 5-(2-methoxy-benzylidene)-3-(tetra-O-acetyl-β-D-glucopyranosyl)-2-thioxo-thiazolidin-4-one
• CAS NO: 65562-25-6
• Molecular Weight: 581.621
• Mol File: 65562-25-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(2-methoxy-benzylidene)-3-(tetra-O-acetyl-β-D-glucopyranosyl)-2-thioxo-thiazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-methoxy-benzylidene)-3-(tetra-O-acetyl-β-D-glucopyranosyl)-2-thioxo-thiazolidin-4-one(65562-25-6)
• EPA Substance Registry System: 5-(2-methoxy-benzylidene)-3-(tetra-O-acetyl-β-D-glucopyranosyl)-2-thioxo-thiazolidin-4-one(65562-25-6)

Safety Data

• Hazardous Substances Data: 65562-25-6(Hazardous Substances Data)

Upstream product

• 73855-60-4 (E,Z)-5-(2-methoxyphenylmethylene)-4-oxo-2-thioxothiazolidine 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 

Relevant articles and documents

N glucopyranosyl 5 aralkylidenerhodanines: Synthesis and antibacterial and antiviral activities

A series of N-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-5-aralkylidenerhodanines was synthesized, and the acetyl groups were removed to give N-β-D-glucopyranosyl-5-aralkylidenerhodanines without cleavage of the rhodanine ring by means of acid hydrolysis. Alkaline hydrolysis with ammonia in methanol resulted in cleavage to N-glucosylthiourea, providing evidence for N-glycoside formation. A number of the rhodanine derivatives, especially those with nitro or chloro groups in the aromatic ring, showed antibacterial activity. N-β-D-Glucopyranosyl-5-(4-nitrobenzylidene)rhodanine showed antiviral activity by inhibition of viral RNA synthesis. Some effect on blood sugar levels also was observed with several rhodanines.