65562-36-9

Basic information

• Product Name: (5E)-5-(1-pyridin-2-ylethylidene)-3-(2,3,4,6-tetra-O-acetylhexopyranosyl)-2-thioxo-1,3-thiazolidin-4-one
• CAS NO: 65562-36-9
• Molecular Formula: C₂₄H₂₆N₂O₁₀S₂
• Molecular Weight: 566.6006
• Mol File: 65562-36-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 637.8°C at 760 mmHg
• Flash Point: 339.5°C
• Density: 1.44g/cm³
• Vapor Pressure: 3.63E-16mmHg at 25°C
• Refractive Index: 1.613
• CAS DataBase Reference: (5E)-5-(1-pyridin-2-ylethylidene)-3-(2,3,4,6-tetra-O-acetylhexopyranosyl)-2-thioxo-1,3-thiazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5E)-5-(1-pyridin-2-ylethylidene)-3-(2,3,4,6-tetra-O-acetylhexopyranosyl)-2-thioxo-1,3-thiazolidin-4-one(65562-36-9)
• EPA Substance Registry System: (5E)-5-(1-pyridin-2-ylethylidene)-3-(2,3,4,6-tetra-O-acetylhexopyranosyl)-2-thioxo-1,3-thiazolidin-4-one(65562-36-9)

Safety Data

• Hazardous Substances Data: 65562-36-9(Hazardous Substances Data)

Usage

Description

(5E)-5-(1-pyridin-2-ylethylidene)-3-(2,3,4,6-tetra-O-acetylhexopyranosyl)-2-thioxo-1,3-thiazolidin-4-one is a complex organic compound featuring a thiazolidin-4-one ring fused with a pyridine group and a hexopyranosyl group. The presence of acetyl groups on the hexopyranosyl moiety adds to its chemical complexity and potential reactivity. This glycosylated thiazolidin-4-one derivative is of interest due to the known biological activities associated with thiazolidin-4-one compounds, such as antimicrobial, antiviral, and antitumor properties. Further research is required to fully understand its specific characteristics and potential applications.

Uses

Used in Pharmaceutical Industry:
(5E)-5-(1-pyridin-2-ylethylidene)-3-(2,3,4,6-tetra-O-acetylhexopyranosyl)-2-thioxo-1,3-thiazolidin-4-one is used as a potential therapeutic agent for its possible antimicrobial, antiviral, and antitumor activities. (5E)-5-(1-pyridin-2-ylethylidene)-3-(2,3,4,6-tetra-O-acetylhexopyranosyl)-2-thioxo-1,3-thiazolidin-4-one's unique structure may offer novel mechanisms of action against various diseases, making it a candidate for further development and testing in the pharmaceutical sector.
Used in Chemical Research:
In the field of chemical research, this compound serves as a subject for studying the synthesis and modification of thiazolidin-4-one derivatives. Its reactivity and the influence of the pyridine and hexopyranosyl groups on its chemical behavior are of particular interest, potentially leading to the discovery of new reactions or applications in organic chemistry.
Used in Material Science:
(5E)-5-(1-pyridin-2-ylethylidene)-3-(2,3,4,6-tetra-O-acetylhexopyranosyl)-2-thioxo-1,3-thiazolidin-4-one's structural features may also make it a candidate for use in material science, where its properties could be harnessed to develop new materials with specific characteristics, such as improved stability or reactivity in certain conditions.

Upstream product

• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 

Relevant articles and documents

N glucopyranosyl 5 aralkylidenerhodanines: Synthesis and antibacterial and antiviral activities

A series of N-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-5-aralkylidenerhodanines was synthesized, and the acetyl groups were removed to give N-β-D-glucopyranosyl-5-aralkylidenerhodanines without cleavage of the rhodanine ring by means of acid hydrolysis. Alkaline hydrolysis with ammonia in methanol resulted in cleavage to N-glucosylthiourea, providing evidence for N-glycoside formation. A number of the rhodanine derivatives, especially those with nitro or chloro groups in the aromatic ring, showed antibacterial activity. N-β-D-Glucopyranosyl-5-(4-nitrobenzylidene)rhodanine showed antiviral activity by inhibition of viral RNA synthesis. Some effect on blood sugar levels also was observed with several rhodanines.