65564-92-3

Basic information

• Product Name: 3-METHYL-3-P-TOLYLCYCLOPENTANONE
• Synonyms: 3-METHYL-3-P-TOLYLCYCLOPENTANONE
• CAS NO: 65564-92-3
• Molecular Formula: C₁₃H₁₆O
• Molecular Weight: 188.27
• Mol File: 65564-92-3.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-METHYL-3-P-TOLYLCYCLOPENTANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-METHYL-3-P-TOLYLCYCLOPENTANONE(65564-92-3)
• EPA Substance Registry System: 3-METHYL-3-P-TOLYLCYCLOPENTANONE(65564-92-3)

Safety Data

• Hazardous Substances Data: 65564-92-3(Hazardous Substances Data)

Upstream product

• 193003-77-9 3-methyl-3-(4-methylphenyl)-1-methylenecyclobutane 
• 2758-18-1 3-Methyl-2-cyclopenten-1-one 
• 15681-48-8 lithium dimethylcuprate 
• 65564-87-6 3-(4-Methylphenyl)-2-cyclopenten-1-one 
• 87306-59-0 2,2-Dichloro-3-methyl-(4-methylphenyl)cyclobutanone 
• 193003-74-6 3-methyl-3-(4-methylphenyl)cyclobutanone 
• 1310492-51-3 C₁₃H₁₈O 
• 927833-56-5 4-methyl-4-(4-methylphenyl)-hepta-1,6-diene 
• 927833-58-7 1-methyl-4-(1-methylcyclopent-3-enyl)benzene 
• 1310492-49-9 (2-methyl-2-(p-tolyl)cyclopropyl)methyl bromide 
• 1310492-50-2 (2-methyl-2-(p-tolyl)cyclopropyl)methanol 
• 6305-61-9 ethyl (E)-3-p-tolylbut-2-enoate 
• 130633-06-6 (E)-3-(4-methylphenyl)-but-2-en-1-ol 
• 122-00-9 para-methylacetophenone 

Downstream Products

• 105556-86-3 (3S)-5-hydroxymethylidene-3-methyl-3-p-tolylcyclopentan-1-one 
• 101693-57-6 (R)-(+)-4-methyl-4-(4-methylphenyl)cyclopent-2-enone 
• 105556-87-4 (3S)-5-n-butylthiomethylidene-3-methyl-3-p-tolylcyclopentan-1-one 
• 51704-29-1 α-cuparenone 
• 16196-32-0 (R)-2,2,3-trimethyl-3-p-tolylcyclopentanone 

Relevant articles and documents

Recoverable polystyrene-supported palladium catalyst for construction of all-carbon quaternary stereocenters via asymmetric 1,4-addition of arylboronic acids to cyclic enones

The development of recoverable catalysts based on the combination of synthetically demanding ligands with transition metals attracts a lot of attention, especially from the environmental point of view. In this paper, we describe the preparation of a recoverable polystyrene supported chiral palladium catalyst based on PyOx ligand suitable for asymmetric 1,4-addition of arylboronic acids to cyclic 3-substituted five- and six-membered enones. In the reaction, all?carbon quaternary stereocenters are formed with a high level of enantioselectivity (up to 91% ee) and conversion (up to 99%). The catalyst was used in 6 cycles with no loss of enantioselectivity and only a small decrease in conversion. A solution of the problems associated with the transition from homogeneous to heterogeneous catalytic systems is discussed.

Stepwise approach for sterically hindered Csp3-Csp3 bond formation by dehydrogenative: O -alkylation and Lewis acid-catalyzed [1,3]-rearrangement towards the arylalkylcyclopentane skeleton of sesquiterpenes

A stepwise dehydrogenative cross-coupling method was developed for the formation of sterically hindered Csp3-Csp3 bonds. Intramolecular dehydrogenative O-alkylation of a β-ketoester by 2,3-dichloro-5,6-dicyano-p-benzoquinone to form an oxolane followed by Lewis acid-catalyzed [1,3]-rearrangement furnished the sesquiterpene arylmethylcyclopentane skeleton. The formal syntheses of herbertane-type β-herbertenol, cuparane-type enokipodins A and B were also achieved.

Efficient formation of benzylic quaternary centers via palladium catalysis

Four's a crowd: An efficient protocol for the formation of benzylic quaternary centers via arylation of enones using a catalyst made from Pd(O 2CCF3)2 and 2,2′-bipyridine is developed. For cyclic substrates, catalyst loadi