65606-47-5

Basic information

• Product Name: 3-Buten-2-one, 4-hydroxy-4-(2-hydroxy-5-methoxyphenyl)-
• Synonyms: 3-Buten-2-one,4-hydroxy-4-(2-hydroxy-5-methoxyphenyl)
• CAS NO: 65606-47-5
• Molecular Formula: C11H12O4
• Molecular Weight: 208.214
• Mol File: 65606-47-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Buten-2-one, 4-hydroxy-4-(2-hydroxy-5-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Buten-2-one, 4-hydroxy-4-(2-hydroxy-5-methoxyphenyl)-(65606-47-5)
• EPA Substance Registry System: 3-Buten-2-one, 4-hydroxy-4-(2-hydroxy-5-methoxyphenyl)-(65606-47-5)

Safety Data

• Hazardous Substances Data: 65606-47-5(Hazardous Substances Data)

Upstream product

• 150-76-5 4-methoxy-phenol 
• 110450-41-4 4-methoxyphenyl 3-(ethylenedioxy)butanoate 
• 110450-48-1 3-(ethylenedioxy)-1-(2-hydroxy-5-methoxyphenyl)-1-butanone 

Relevant articles and documents

New photochemical approaches to the synthesis of chromones

Irradiation of the p-methoxyphenyl and p-methylphenyl esters of 2-butynoic, propynoic, 3-(ethylenedioxy)butanoic, 3,3-dimethoxypropanoic and 3-oxobutanoic acids (1-3) affords the corresponding photo-Fries products 4-6. Compound 5a is converted in part into the acetophenone 7a, by way of a Norrish type II photo-reaction, while compound 6a is reluctant to undergo this process, in spite of the fact that it also possess γ-carbonyl hydrogen atoms. From the preparative point of view, the photorearrangement of the esters 1a-d and 2a,c-d is exploitable, while that of 3a proceeds with a lower yield. The differences found in the photochemical behaviour of 2a and 3a show the sharp influence of the acetal group on the course of the reaction. Compounds 4-6 are representative model compounds valuable as direct chromone precursors; in fact, they can be readily cyclized to the chromones 10 under basic or acidic conditions.