65662-59-1

Basic information

• Product Name: 1-Propanone, 1-(4-methoxyphenyl)-2-nitro-
• CAS NO: 65662-59-1
• Molecular Formula: C10H11NO4
• Molecular Weight: 209.202
• Mol File: 65662-59-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 1-(4-methoxyphenyl)-2-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 1-(4-methoxyphenyl)-2-nitro-(65662-59-1)
• EPA Substance Registry System: 1-Propanone, 1-(4-methoxyphenyl)-2-nitro-(65662-59-1)

Safety Data

• Hazardous Substances Data: 65662-59-1(Hazardous Substances Data)

Usage

Uses

Synthesis of various pharmaceuticals and organic compounds

Compound type

Organic nitro compound, ketone

Aromatic compound

Yes, with a 4-methoxyphenyl group

Nitro group position

Attached to the beta carbon of the ketone group

Reactivity

Highly reactive, suitable for use in organic synthesis

Hazardous nature

Potentially hazardous, should be handled with care

Upstream product

• 148527-33-7 2-nitro-1-hydroxy-1-(4-methoxy-phenyl)-propane 
• 59518-26-2 cyanodinitroethoxycarbonyl methane 
• 104-46-1 anethole 
• 1840-42-2 fluorotrinitromethane 

Downstream Products

• 121-97-1 4-Methoxypropiophenone 
• 1589528-65-3 (E)-1-(4-methoxyphenyl)-2-methyl-2-nitro-5-phenylpent-4-en-1-one 
• 5344-83-2 2-(hydroxyimino-(seqtrans))-1-(4-methoxy-phenyl)-propanone-⁽¹⁾ 

Relevant articles and documents

A high performance oxidation method for secondary alcohols by inductive activation of TEMPO in combination with pyridine-bromine complexes

A new TEMPO-mediated catalytic oxidation method in combination with Py·HBr3 (stoichiometric) is developed for oxidation of secondary alcohols to the corresponding ketones. The performance of this oxidizing system is better compared with that of TEMPO method combined with R4NBr3. Poly(4-vinylpyridine)·HBr3 can be used in place of Py·HBr3. The electron-withdrawing substituent at the C-4 position of TEMPO increases the reactivity of TEMPO significantly in the oxidation of electron-deficient alcohols such as polyhaloalkylmethanols. Inductive effect of the substituent of TEMPO is discussed through the characterization of the redox potential of N-O radical by cyclic voltammetry.

1-BENZYL-1,4-DIHYDRONICOTINAMIDE AS A REAGENT FOR REPLACING ALIPHATIC NITRO GROUPS BY HYDROGEN. AN ELECTRON-TRANSFER CHAIN REACTION.

The reaction of alpha -nitro nitriles, alpha -nitro esters, and alpha -nitro ketones with 1-benzyl-1,4-dihydronicotinamide (BNAH) can occur with selective replacement of the nitro group by hydrogen without affecting other functional groups. Evidence is presented to support the claim that the reaction proceeds via an electron-transfer chain mechanism in which radical anions and free radicals are intermediates.