65671-10-5 Usage
Description
[[2-Nitro-5-(propylthio)phenyl]thiocarbamoyl]carbamic acid methyl ester is an organic compound that serves as a key intermediate in the synthesis of various pharmaceutical agents. Its unique chemical structure, featuring a nitro group, a propylthio substituent, and a thiocarbamoyl linkage, endows it with specific reactivity and properties that are valuable in the development of therapeutic compounds.
Uses
Used in Pharmaceutical Industry:
[[2-Nitro-5-(propylthio)phenyl]thiocarbamoyl]carbamic acid methyl ester is used as a synthetic intermediate for the production of Netobimin (N390900), a phenylguanidine anthelmintic agent. It plays a crucial role in the synthesis process, contributing to the development of this medication that targets and eliminates parasitic worms, particularly in veterinary medicine.
As an intermediate, [[2-Nitro-5-(propylthio)phenyl]thiocarbamoyl]carbamic acid methyl ester is instrumental in the creation of active pharmaceutical ingredients (APIs) that can be further processed or combined with other compounds to form effective treatments for various medical conditions. Its presence in the synthesis of Netobimin highlights its potential in contributing to the development of anthelmintic drugs, which are essential for treating infections caused by parasitic worms in both humans and animals.
Check Digit Verification of cas no
The CAS Registry Mumber 65671-10-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,6,7 and 1 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 65671-10:
(7*6)+(6*5)+(5*6)+(4*7)+(3*1)+(2*1)+(1*0)=135
135 % 10 = 5
So 65671-10-5 is a valid CAS Registry Number.
65671-10-5Relevant articles and documents
Preparation of N-methoxycarbonyl-N'-[2-nitro-4(5)-propyl-thiophenyl]thiourea as prodrugs of albendazole
Hernandez-Luis, Francisco,Castillo, Rafael,Yepez-Mulia, Lilian,Cedillo-Rivera, Roberto,Martinez-Vazquez, Gabriel,Morales-Hurtado, Raul,Jung, Helgi,Sanchez, Monica,Hernandez-Campos, Alicia,Viveros, Noemi,Munoz, Onofre
, p. 2231 - 2236 (2007/10/03)
N-methoxycarbonyl-N'-(2-nitro-4-propylthiophenyl)thiourea and N-methoxycarbonyl-N'-(2-nitro-5-propylthiophenyl)thiourea, prodrugs of albendazole, have been synthesized. The biotransformation in rats, after oral administration of these prodrugs to albendazole and albendazole sulphoxide, is described.
