65679-28-9

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 2-phenyl-7-(2-propenyloxy)-
• CAS NO: 65679-28-9
• Molecular Formula: C18H14O3
• Molecular Weight: 278.307
• Mol File: 65679-28-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 2-phenyl-7-(2-propenyloxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 2-phenyl-7-(2-propenyloxy)-(65679-28-9)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 2-phenyl-7-(2-propenyloxy)-(65679-28-9)

Safety Data

• Hazardous Substances Data: 65679-28-9(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 40815-74-5 4-allyloxy-2-hydroxyacetophenone 
• 100-52-7 benzaldehyde 
• 6665-86-7 7-hydroxyflavone 
• 106-95-6 allyl bromide 

Downstream Products

• 691008-31-8 2-phenyl-8-(prop-2-en-1-yl)-7-(prop-2-en-1-yloxy)-4H-1-benzopyran-4-one 
• 63455-98-1 8-allyl-7-hydroxy-2-phenyl-chromen-4-one 

Relevant articles and documents

Synthesis of Diverse Oxa-Carbocycle-Annulated Flavones Using the Combined Claisen Rearrangement and Ring-Closing Metathesis

A simple and efficient route for the synthesis of oxepine-, oxocine-, oxepinone-, and dioxocine-angularly annulated flavone skeletons has been developed. The combined Claisen rearrangement and the ring-closing metathesis are used as key steps for the construction of C7/C8–C6–C6tricyclic core structures.

A facile synthesis of 2,3-dihydro-2-hydroxymethyl-5-arylfuro[2,3-h][1]benzopyran-7-ones

The reaction of various 7-hydroxyflavones (1) with allyl bromide in potassium carbonate-acetone yielded the corresponding 7-allyloxy derivatives (2). Claisen rearrangement of 2 gives 7-hydroxy-8-allylflavones (3) which on reaction with equimolar quantity of mCPBA in dichloromethane furnish regioselectively 2,3-dihydro-2-hydroxymethyl-5-aryl-furo[2,3-h][1]benzopyran-7-ones (5) in good yields.