65725-06-6

Basic information

• Product Name: T-2 TETRAOL TETRAACETATE
• Synonyms: 12,13-epoxytrichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetroltetraacetate;4-beta,8-alpha,15-tetrol,12,13-epoxy-trichothec-9-ene-3-alphtetracetate;diacetylneosolaniol;neosolanioldiacetate;t-2tetra-acetate;t-2tetraoltetraacetate;TETRAOLTETRA-ACETATE
• CAS NO: 65725-06-6
• Molecular Formula: C24H32O9
• Molecular Weight: 464.508
• Mol File: 65725-06-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 522.5°Cat760mmHg
• Flash Point: 223.6°C
• Appearance: /
• Density: 1.32g/cm³
• Vapor Pressure: 5.15E-11mmHg at 25°C
• Refractive Index: 1.542
• Storage Temp.: ?20°C
• CAS DataBase Reference: T-2 TETRAOL TETRAACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: T-2 TETRAOL TETRAACETATE(65725-06-6)
• EPA Substance Registry System: T-2 TETRAOL TETRAACETATE(65725-06-6)

Safety Data

• Hazard Codes: T+
• Statements: 26/27/28-36/37/38
• Safety Statements: 22-36/37/39-45
• Hazardous Substances Data: 65725-06-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C23H30O10/c1-11-7-17-22(9-28-12(2)24,8-16(11)30-13(3)25)21(6)19(32-15(5)27)18(31-14(4)26)20(33-17)23(21)10-29-23/h7,16-20H,8-10H2,1-6H3/t16-,17+,18+,19+,20+,21?,22+,23?/m0/s1

Upstream product

• 36519-25-2 Neosolaniol 
• 127-09-3 sodium acetate 
• 81331-39-7 4β,15-Diacetoxy-8β-bromo-12,13-epoxytrichothec-9-en-3α-ol 
• 108-24-7 acetic anhydride 
• 68165-53-7 C₂₁H₂₈O₉ 
• 130819-41-9 C₁₇H₂₆O₅ 
• 130819-40-8 C₁₈H₂₆O₆ 
• 130819-44-2 C₂₃H₄₂O₇Si 
• 130819-50-0 (1S,2R,5R,7R,10R,11S)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-10,11-dihydroxy-1,5-dimethyl-12-methylene-8-oxa-tricyclo[7.2.1.0^2,7]dodecan-4-one 
• 130819-43-1 C₂₃H₄₀O₅Si 
• 130829-20-8 C₂₃H₄₀O₅Si 
• 130829-22-0 C₂₁H₃₆O₆Si 
• 130819-48-6 C₂₃H₃₈O₅Si 
• 130819-45-3 C₂₂H₃₈O₆Si 

Relevant articles and documents

Phytotoxic Compounds Produced by Fusarium equiseti. Part 10. The Preparation and Rearrangement of Diacetylneosolaniol 9β,10β-epoxide

Under conditions where trichothecodiol 9β,10β-epoxide rearranges to an 8α,9α:10β,13-diepoxytrichothecan-12-ol, diacetylneosolaniol 9β,10β-epoxide gives a 9α,15:12,13-diepoxytrichothecan-10β-ol.Some by-products formed during the allylic bromination and allylic oxidation od diacetoxyscirpenol have been identified.One of them is a 3α,11α:12,13-diepoxytrichothecene.

Structure-Activity Studies of Trichothecenes: Cytotoxicity of Analogues and Reaction Products Derived from T-2 Toxine and Neosolaniol

Forty-two analogues and reaction products derived from T-2 toxin or neosolaniol were assayed for their cytotoxicity to cultured mouse lymphoma cells.Structure-activity relationships confirmed the stereospecific nature of the cytotoxic action of T-2.Cytoto