657393-24-3

Basic information

• Product Name: 1,2-Propanediol, 1-(3,4,5-trimethoxyphenyl)-, (1R,2R)-
• CAS NO: 657393-24-3
• Molecular Formula: C12H18O5
• Molecular Weight: 242.272
• Mol File: 657393-24-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,2-Propanediol, 1-(3,4,5-trimethoxyphenyl)-, (1R,2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Propanediol, 1-(3,4,5-trimethoxyphenyl)-, (1R,2R)-(657393-24-3)
• EPA Substance Registry System: 1,2-Propanediol, 1-(3,4,5-trimethoxyphenyl)-, (1R,2R)-(657393-24-3)

Safety Data

• Hazardous Substances Data: 657393-24-3(Hazardous Substances Data)

Upstream product

• 5438-54-0 1,3-dimethoxy-2-[(prop-2-en-1-yl)oxy]benzene 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 91-10-1 1,3-dimethoxy-2-hydroxy-benzene 
• 20675-95-0 (E)-2,6,-dimethoxy-4-(prop-1-en-1-yl)phenol 
• 487-12-7 isoelemicin 

Downstream Products

• 835922-46-8 (R)-1-(3,4,5-trimethoxyphenyl)-2-propanol 
• 657393-34-5 (E)-3-{3-methoxy-4-[(1S)-methyl-2-oxo-2-(3,4,5-trimethoxy-phenyl)-ethoxy]-phenyl}-acrylic acid ethyl ester 
• 657393-29-8 (2S)-(2,6-dimethoxy-4-propenyl-phenoxy)-1-(3,4,5-trimethoxy-phenyl)-propan-1-one 
• 657393-36-7 (2S)-((E)-2-ethoxy-5-propenyl-phenoxy)-1-(3,4,5-trimethoxy-phenyl)-propan-1-one 
• 657393-32-3 (2S)-[4-((E)-styryl)-phenoxy]-1-(3,4,5-trimethoxy-phenyl)-propan-1-one 
• 657393-28-7 toluene-4-sulfonic acid (1R)-methyl-2-oxo-2-(3,4,5-trimethoxy-phenyl)-ethyl ester 
• 443684-50-2 (2R)-hydroxy-1-(3,4,5-trimethoxy-phenyl)-propan-1-one 

Relevant articles and documents

Concise access toward chiral hydroxy phenylpropanoids: formal synthesis of virolongin B; kigelin; kurasoin A; 4-hydroxysattabacin, and actinopolymorphol A

A simple, two step strategy consisting of Sharpless asymmetric dihydroxylation followed by regioselective breaking of [Formula presented] bond is utilized to target key chiral intermediates of natural products virolongin B, kigelin, kurasoin A, 4-hydroxy-sattabacin, and actinopolymorphol A. Derivatives of enantiopure hydroxy phenyl propanoids and α-hydroxy Weinreb amides are synthesized. The reductive cleavage of [Formula presented] bond in a regioselective manner is obtained using Pd/C in methanol.