65763-00-0

Basic information

• Product Name: 7-hydroxy-8-iodo-2H-chromen-2-one
• Synonyms: 2H-1-Benzopyran-2-one, 7-hydroxy-8-iodo-; 7-Hydroxy-8-iodocoumarin
• CAS NO: 65763-00-0
• Molecular Formula: C₉H₅IO₃
• Molecular Weight: 288.0387
• Mol File: 65763-00-0.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 371.6°C at 760 mmHg
• Flash Point: 178.5°C
• Density: 2.093g/cm³
• Vapor Pressure: 4.76E-06mmHg at 25°C
• Refractive Index: 1.723
• CAS DataBase Reference: 7-hydroxy-8-iodo-2H-chromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-hydroxy-8-iodo-2H-chromen-2-one(65763-00-0)
• EPA Substance Registry System: 7-hydroxy-8-iodo-2H-chromen-2-one(65763-00-0)

Safety Data

• Hazardous Substances Data: 65763-00-0(Hazardous Substances Data)

Upstream product

• 93-35-6 7-hydroxy-2H-chromen-2-one 
• 92439-17-3 2-<3,4-Dihydroxy-phenyl>-chromen-7-on, Anhydro-7,3',4'-trihydroxy-flaven-(4 oder 2)-ol 
• 76463-89-3 7-allyloxy-8-iodo-2H-1-benzopyran-2-one 

Downstream Products

• 1891-25-4 8-(2-hydroxypropan-2-yl)-2H-furo[2,3-h]chromen-2-one 
• 143882-70-6 7-cinnamyloxy-8-iodocoumarin 
• 1760-27-6 oroselone 
• 159979-58-5 7-Benzyloxy-8-iodo-chromen-2-one 
• 6545-99-9 8-(3-isopropenyloxiran-2-yl)-7-methoxy-2H-chromen-2-one 
• 6724-42-1 7-methoxy-2-oxo-2H-chromene-8-carbaldehyde 
• 112606-76-5 osthenon 
• 159979-59-6 7-Benzyloxy-8-((E)-3-hydroxy-3-methyl-but-1-enyl)-chromen-2-one 
• 159979-60-9 7-Benzyloxy-8-((1S,2R)-1,2,3-trihydroxy-3-methyl-butyl)-chromen-2-one 
• 13164-04-0 2,3-dihydro-2-(2-hydroxypropan-2-yl)-6-(2-methylbut-3-en-2-yl)furo[3,2-g]chromen-7-one 
• 14882-94-1 (+/-)-rutamarin 
• 484-14-0 osthenol 
• 143882-67-1 7-hydroxy-8-(1'-phenylprop-2'-ene)coumarin 
• 143882-71-7 7-hydroxy-6-(1'-phenylprop-2'-one)coumarin 

Relevant articles and documents

Concise and scalable synthesis of xanthylentin

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Osthole derivatives and preparation method and application thereof

The invention relates to osthole derivatives, and a preparation method and application thereof, and belongs to the technical field of organic chemistry. The technical problem to be solved by the present invention is to provide the novel osthole derivatives. The isopentene group on the No.8 site of osthole is modified and transformed to obtain a series of the osthole derivatives having bacteriostatic effects, and the structures of the derivatives are shown as a formula I. The derivatives are chemically synthesized from 7-hydroxycoumarin with a simple preparation process and a high yield, and the obtained products have good bacteriostatic effects, and can be used for plant disease control, especially for control of plant anthracnose, late blight, brown speckle disease or gray mold.

Synthesis of osthole derivatives with grignard reagents and their larvicidal activities on mosquitoes

The structure of osthole has been modified to improve its larvicidal activity against mosquitoes. A new efficient synthesis of osthole derivatives with Grignard reagents has been developed, which employs CuI and LiCl as promoters and covers a broad range of substrates to afford the corresponding products in mild to good yields (up to 83%). Bio-activity evaluation showed that several products exhibited better activities than osthole. CuI and LiCl promoted efficient synthesis of osthole derivatives with Grignard reagents has been developed. Bio-activity evaluation showed that several products exhibited far better larvicidal activities against mosquitoes than osthole.