65837-37-8

Basic information

• Product Name: 1H-Indole, 6-bromo-2,3-diphenyl-
• CAS NO: 65837-37-8
• Molecular Formula: C20H14BrN
• Molecular Weight: 348.242
• Mol File: 65837-37-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 6-bromo-2,3-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 6-bromo-2,3-diphenyl-(65837-37-8)
• EPA Substance Registry System: 1H-Indole, 6-bromo-2,3-diphenyl-(65837-37-8)

Safety Data

• Hazardous Substances Data: 65837-37-8(Hazardous Substances Data)

Upstream product

• 27246-81-7 3-bromophenylhydrazine hydrochloride 
• 501-65-5 diphenyl acetylene 
• 591-19-5 m-Bromoaniline 
• 1239-56-1 1-(2,3-diphenyl-1H-indol-1-yl)ethan-1-one 
• 859965-90-5 1-acetyl-6-bromo-2,3-diphenyl-indole 

Relevant articles and documents

Regioselective synthesis of indoles via rhodium-catalyzed C-H activation directed by an in-situ generated redox-neutral group

A regioselective synthesis of indoles from arylhydrazine hydrochlorides with alkynes and diethyl ketone catalyzed by a rhodium complex is described. A possible mechanism involving an in-situ generated oxidizing directing group -N-Ni'CR1R2 assisted ortho-C-H activation and reductive elimination are proposed. The catalytic reaction is highly compatible with a wide range of functional arylhydrazines and alkynes. The reaction proceeds under mild reaction conditions and is atom-step economical.

Palladium-catalyzed reaction of arylamine and diarylacetylene: Solvent-controlled construction of 2,3-diarylindoles and pentaarylpyrroles

By choosing DMF and dioxane as solvent, skeletons of indoles and pyrroles were constructed from alkynes and amines in the presence of PdCl2, respectively. These Pd-catalyzed reactions were phosphane-free with high atom efficiency and could be conducted under mild basic conditions. The proposed mechanism for the selective formation of indoles and pyrroles in different solvents is also discussed in this paper. Two different kinds of Pd-catalyzed cyclizations, leading to the construction of 2,3-diarylindole and pentaarylpyrrole from the same alkyne and aniline starting materials, were approached by choosing different solvents. The mechanisms for these solvent-controlled reactions are proposed and discussed. Copyright