65865-28-3 Usage
General Description
[5-(Trifluoromethyl)-2-furyl]methanol, also known as 5-TFMF, is a chemical compound with the molecular formula C7H5F3O2. It is a colorless liquid at room temperature and is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. 5-TFMF has a furanyl group and a trifluoromethyl group, making it useful for introducing these functional groups into target molecules. It is also used as a solvent in organic synthesis and as an intermediate in the production of other organic compounds. The compound has been studied for its potential biological activities and has shown promise as an anti-inflammatory and anti-cancer agent. However, its toxicological properties are not well understood, and caution should be exercised when handling and using 5-TFMF.
Check Digit Verification of cas no
The CAS Registry Mumber 65865-28-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,8,6 and 5 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 65865-28:
(7*6)+(6*5)+(5*8)+(4*6)+(3*5)+(2*2)+(1*8)=163
163 % 10 = 3
So 65865-28-3 is a valid CAS Registry Number.
65865-28-3Relevant articles and documents
Grigorash et al.
, (1977)
THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS
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Page 245, (2008/06/13)
Disclosed are novel compounds of the formula (IA) and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and cardiac reperfusion injury, acute pain, acute and chronic inflammatory pain, and neuropathic pain using a compound of formula (IA).
3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands
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Page 126, (2008/06/13)
There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.