658712-69-7 Usage
Type of compound
Carboxylic acid derivative
Structure
Piperidine ring system with a methyl group and a phenyl group
Usage in medicinal chemistry research
Starting material for the synthesis of various pharmaceuticals and biologically active compounds
Potential applications
Development of new drugs for the treatment of neurological disorders, synthesis of compounds with analgesic properties
Additional studies
Use as a chiral auxiliary, building block for the synthesis of bioactive molecules
Check Digit Verification of cas no
The CAS Registry Mumber 658712-69-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,8,7,1 and 2 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 658712-69:
(8*6)+(7*5)+(6*8)+(5*7)+(4*1)+(3*2)+(2*6)+(1*9)=197
197 % 10 = 7
So 658712-69-7 is a valid CAS Registry Number.
658712-69-7Relevant articles and documents
A concise synthesis of an indenopyrrolidine-based dual α vβ3/αvβ5 integrin antagonist
Luci, Diane K.,Santulli, Rosemary J.,Gauthier, Diane A.,Tounge, Brett A.,Ghosh, Shyamali,Proost, Jef C.,Kinney, William A.,De Corte, Bart,Galemmo Jr., Robert A.,Lewis, Joan M.,Dorsch, Warren E.,Wagaman, Michael W.,Damiano, Bruce P.,Maryanoff, Bruce E.
, p. 543 - 557 (2007/10/03)
A new class of dual αVβ3/α Vβ5 integrin antagonists containing a central cis-fused cyclopentane ring was identified. Because of its increased structural rigidity, the indenopyrrolidine ring system provides insight into the active conformation of other αVβ3 ligands. A concise synthesis of the indenopyrrolidine ring system was accomplished by 1,3-dipolar cycloaddition. Individual isomers of the most active compound were separated by chiral HPLC and their biological activities were compared.
