65878-65-1

Basic information

• Product Name: (2S,3R)-threo-2-phenylpentan-3-ol
• Synonyms: (2S,3R)-threo-2-phenylpentan-3-ol
• CAS NO: 65878-65-1
• Molecular Weight: 164.247
• Mol File: 65878-65-1.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: (2S,3R)-threo-2-phenylpentan-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R)-threo-2-phenylpentan-3-ol(65878-65-1)
• EPA Substance Registry System: (2S,3R)-threo-2-phenylpentan-3-ol(65878-65-1)

Safety Data

• Hazardous Substances Data: 65878-65-1(Hazardous Substances Data)

Upstream product

• 10467-10-4 ethylmagnesium iodide 
• 93-53-8 (S)-2-phenyl-propionaldehyde 
• 34713-70-7 2-Phenylpropanal 
• 63801-22-9 2-phenylpentan-3-one 
• 2397-68-4 sodium tetraethylaluminate 
• 78-00-2 tetraethyllead(IV) 
• 557-20-0 diethylzinc 
• 925-90-6 ethylmagnesium bromide 
• 103130-62-7 (2S)-2-phenylpentan-3-one 
• 22293-10-3 (1-diazoethyl)benzene 
• 13466-30-3 (1-phenylethylidene)hydrazine 
• 36041-82-4 methyl (3R,4S)-3-hydroxy-4-phenylpentanoate 

Downstream Products

• 75724-31-1 (+/-)-threo-3-(3.5-dinitro-benzoyloxy)-2-phenyl-pentane 
• 75724-23-1 cyclohexyl-2 pentanol-3 
• 75724-23-1 cyclohexyl-2 pentanol-3 
• 127181-69-5 (2R,3R)-erythro-2-phenylpentan-3-ol 
• 24663-49-8 DL-erythro-2-Phenyl-pentyl-⁽³⁾-methansulfonat 

Relevant articles and documents

Catalytic Asymmetric Formal Insertion of Aryldiazoalkanes into the C-H Bond of Aldehydes: Synthesis of Enantioenriched Acyclic α-Tertiary Aryl Ketones

A novel, catalytic enantioselective route to synthesize a variety of α-tertiary aryl ketones via a boron Lewis acid promoted formal insertion of aryldiazoalkane into the C-H bond of both aromatic and aliphatic aldehydes is described. In the presence of ch

[1,2]-Wittig rearrangement of enantio-defined α-alkoxyalkyllithiums: Structural requirement and steric course at the Li-bearing terminus

The [1,2]-Wittig rearrangements of enantio-defined α-benzyloxypropyllithium and its (R)-α-methylbenzyloxy analogs, generated from the enantio-enriched stannanes via Sn/Li exchange, are shown to proceed predominantly with inversion of configuration at the

A new type of complex reagent, R4Pb / TiCl4

Tetraalkllleads (R4Pb) reacted quite smoothly with aldehydes R'CHO in the presence of TiCl4 to produce the corresponding alcohols (RCHOHR′) in high to good yields. The reagent system, R4Pb/ TiCl4, exhibited high chemoselectivity; only aldehydes underwent the alkylation in the presence of ketones. Further, the new reagent exhibited high 1,2- and 1,3-asymmetric induction. The transfer order of alkyl groups in the reaction of aldehydes with mixed tetraalkylleads/TiCl4 was determined; Me>Et.i-Pr?n-Bu.