659-00-7

Basic information

• Product Name: 2-(ethylsulfanyl)-5-fluoropyrimidin-4(3H)-one
• Synonyms: 4(3H)-pyrimidinone, 2-(ethylthio)-5-fluoro-
• CAS NO: 659-00-7
• Molecular Formula: C₆H₇FN₂OS
• Molecular Weight: 174.196
• Mol File: 659-00-7.mol
• Article Data: 2

Chemical Properties

• Density: 1.4g/cm³
• Refractive Index: 1.595
• CAS DataBase Reference: 2-(ethylsulfanyl)-5-fluoropyrimidin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(ethylsulfanyl)-5-fluoropyrimidin-4(3H)-one(659-00-7)
• EPA Substance Registry System: 2-(ethylsulfanyl)-5-fluoropyrimidin-4(3H)-one(659-00-7)

Safety Data

• Hazardous Substances Data: 659-00-7(Hazardous Substances Data)

Usage

Chemical Class

Pyrimidine derivatives

Type of Compound

Synthetic chemical

Potential Properties

Antineoplastic and antiviral

Biological Activity

Contributed by a fluorine atom and an ethylsulfanyl group attached to the pyrimidine ring

Potential Applications

Development of new drugs for the treatment of various diseases, including cancer and viral infections

Additional Research Needed

To fully understand the pharmacological properties and potential therapeutic uses of the compound.

Upstream product

• 81560-10-3 2-ethylthio-4-benzyloxy-5-fluoropyrimidine 
• 104705-25-1 2-ethylthio-5-fluoro-4-methoxypyrimidine 
• 104705-26-2 2,4-diethylthio-5-fluoropyrimidine 

Downstream Products

• 51-21-8 5-fluorouracil 
• 81560-10-3 2-ethylthio-4-benzyloxy-5-fluoropyrimidine 
• 81560-07-8 2-ethylthio-3-benzyl-5-fluoropyrimidin-4-one 
• 81560-04-5 1-benzyl-2-ethylthio-5-fluoropyrimidin-4-one 

Relevant articles and documents

Chemoselectivity and Regoselectivity in Reactions of Pyrimidines

Selective nucleophilic substitution and hydrogenolysis reactions in pyrimidines are discussed.Stepwise oxidation reactions of pyrimidine sulfides and HPLC studies of these are reported.