65921-30-4

Basic information

• Product Name: 2-(4-nitrophenyl)-2-oxoethyl acetate
• Synonyms: 2-(4-nitrophenyl)-2-oxoethyl acetate;Ethanone, 2-(acetyloxy)-1-(4-nitrophenyl)-
• CAS NO: 65921-30-4
• Molecular Formula: C₁₀H₉NO₅
• Molecular Weight: 223.19
• Mol File: 65921-30-4.mol
• Article Data: 12

Chemical Properties

• Melting Point: 122-124°
• Boiling Point: 352.3°C at 760 mmHg
• Flash Point: 163.2°C
• Appearance: /
• Density: 1.318g/cm³
• Vapor Pressure: 3.86E-05mmHg at 25°C
• Refractive Index: 1.549
• CAS DataBase Reference: 2-(4-nitrophenyl)-2-oxoethyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-nitrophenyl)-2-oxoethyl acetate(65921-30-4)
• EPA Substance Registry System: 2-(4-nitrophenyl)-2-oxoethyl acetate(65921-30-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 65921-30-4(Hazardous Substances Data)

Usage

General Description

2-(4-Nitrophenyl)-2-oxoethyl acetate is a chemical compound with the molecular formula C10H9NO5. This chemical belongs to the group of phenols and derivatives. The 2-(4-nitrophenyl)-2-oxoethyl acetate is relatively stable, but can react with strong oxidizing agents. In general, this chemical is used in various scientific research works and organic syntheses. Its detailed characteristics, including solubility, physical state, and toxicity, are subject to the specifications of each particular commercial product. As with all chemicals, it should be handled with care and disposed of properly.

InChI:InChI=1/C10H9NO5/c1-7(12)16-6-10(13)8-2-4-9(5-3-8)11(14)15/h2-5H,6H2,1H3

Upstream product

• 34006-49-0 2-chloro-1-(4-nitrophenyl)ethanone 
• 127-09-3 sodium acetate 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 100-19-6 (4-nitrophenyl)ethanone 
• 108-24-7 acetic anhydride 
• 99-81-0 4-Nitrophenacyl bromide 
• 127-19-5 N,N-dimethyl acetamide 
• 127-08-2 potassium acetate 
• 937-31-5 (4-Nitrophenyl)acetylene 
• 71-50-1 acetate 

Downstream Products

• 14922-36-2 4-nitrophenylglyoxylic acid 
• 77977-74-3 (S)-(+)-1-(4-nitrophenyl)-1,2-ethanediol 
• 77977-74-3 (R)-(-)-1-(4-nitrophenyl)-1,2-ethanediol 
• 287944-34-7 (S)-(+)-1-(4-aminophenyl)-1,2-ethanediol 
• 287944-27-8 (S)-(+)-N-(4-(1,2-dihydroxyethyl)phenyl)methanesulfonamide 
• 1239347-32-0 2-acetoxymethyl-2-(4-nitrophenyl)-2,3-dihydroquinazolin-4(1H)-one 
• 62830-97-1 2-(4-aminophenyl)-2-oxoethyl acetate 
• 99282-59-4 1-(4-aminophenyl)-2-hydroxyethan-1-one 
• 501693-47-6 4-amino-3-(4-aminophenyl)furo[2,3-d]pyrimidine 

Relevant articles and documents

Imidazolium-Based Ionic Network as a Robust Heterogeneous Catalyst in Synthesis of Phenacyl Derivatives

A new imidazolium-based poly(ionic liquid) has been synthesized and used as a robust heterogeneous catalyst for the preparation of phenacyl derivatives by an SN2 reaction of different phenacyl bromides with a broad range of nucleophiles. The products are obtained in high yields under mild conditions. The catalyst can be recycled efficiently.

Novel and efficient transformation of enamides into α-acyloxy ketones via an acyl intramolecular migration process

Hydrogen peroxide and anhydride mediated transformation of enamides to afford substituted α-acyloxy ketones is described. This transition-metal-free cascade reaction has a broad substrate scope and high efficiency. The acyl intramolecular migration procedure successfully achieved this acyloxylation process under mild conditions and increased the atom efficiency.

Integration of aqueous biphasic with magnetically recyclable systems: Polyethylene glycol-grafted Fe3O4 nanoparticles catalyzed phenacyl synthesis in water

The present work trends to define an efficient phenacyl catalytic synthesis method employing a new nano-magnetite-supported organocatalyst. Polyethylene glycol (PEG) was bonded successfully onto silica coated ferrite and the resultant nanoparticles (PEG@SiO2@Fe3O4) characterized by fourier transform infrared spectroscopy (FT-IR), atomic force microscopy (AFM), thermal gravimetric analysis (TGA), vibrating sample magnetometry (VSM), energy dispersive X-ray analysis (EDAX) and X-ray diffraction (XRD) that exhibited a good catalytic activity in the reaction. The nanoparticles could be easily separated from the reaction mixture by an external magnet and reused in seven reaction cycles without significant loss of activity.