65977-55-1 Usage
General Description
5-Chlorothieno[3,2-b]pyridine is a chemical compound with the molecular formula C8H4ClNS. Belonging to the category of thieopyridines, this chemical is characterized by its chlorine atom and fused ring structure. In the world of organic synthetic chemistry, 5-chlorothieno[3,2-b]pyridine acts primarily as a building block, used in the creation of more complex chemical compounds. It can also find application in pharmaceutical industries for the preparation of various drug molecules. However, beyond its elemental structure and uses, information about this specific chemical, such as its physical properties and safety data, appears to be limited in publicly accessible scientific literature.
Check Digit Verification of cas no
The CAS Registry Mumber 65977-55-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,9,7 and 7 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 65977-55:
(7*6)+(6*5)+(5*9)+(4*7)+(3*7)+(2*5)+(1*5)=181
181 % 10 = 1
So 65977-55-1 is a valid CAS Registry Number.
65977-55-1Relevant articles and documents
Chemistry of Thienopyridines. XXXIII. Synthetic Routes to 5- and 7-Substituted Thienopyridines from the N-Oxide
Klemm, L. H.,Louris, John N.,Boisvert, William,Higgins, Clay,Muchiri, Daniel R.
, p. 1249 - 1252 (2007/10/02)
Thienopyridine (1) is oxidized to N-oxide 1a by means of m-chloroperoxybenzoic acid (83percent).Compound 1a forms adducts with hydrogen chloride and picric acid and gives ring substitution alpha or gamma to the heteronitrogen atom.Thus, 1a plus nitric and sulfuric acids produces the 7-nitro-N-oxide 1m (63percent), or plus phosphorus oxychloride gives a mixture of 5-chloro and 7-chloro (1j) derivatives of 1.Compound 1m is convertible into a variety of other derivatives of 1, viz 7-chloro-N-oxide, 1j, 7-bromo-N-oxide, 7-nitro and 7-amino. 5-Cyano-1, formed from 1a, is, in turn, transformed into a methyl imidate (93percent), cyclic amidines, and a 5-tetrazolyl-1 (91percent).These results confirm the prediction that 1a, thienopyridine-4-oxide and quinoline 1-oxide should exhibit closely similar (i.e. analogous) chemical reactions.
