65984-59-0

Basic information

• Product Name: 3-(4-bromophenyl)-3-hydroxypropanenitrile
• Synonyms: 3-(4-bromophenyl)-3-hydroxypropanenitrile
• CAS NO: 65984-59-0
• Molecular Weight: 226.073
• Mol File: 65984-59-0.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 3-(4-bromophenyl)-3-hydroxypropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-bromophenyl)-3-hydroxypropanenitrile(65984-59-0)
• EPA Substance Registry System: 3-(4-bromophenyl)-3-hydroxypropanenitrile(65984-59-0)

Safety Data

• Hazardous Substances Data: 65984-59-0(Hazardous Substances Data)

Usage

Functional Groups

Nitrile (-CN), Hydroxy (-OH), Bromo (-Br), Phenyl (-C6H5)

Use

Synthesis of pharmaceuticals and organic compounds

Applications

Building block for biologically active molecules, potential in medicinal chemistry

Reactivity

Diverse reactivity, valuable in organic synthesis and drug development

Upstream product

• 4592-94-3 3-(4-bromophenyl)-3-oxopropanenitrile 
• 111873-50-8 dibutyl(cyanomethyl)telluronium chloride 
• 1122-91-4 4-bromo-benzaldehyde 
• 590-17-0 cyanomethyl bromide 
• 75-05-8 acetonitrile 
• 1124-14-7 1-bromo-4-cyclopropylbenzene 
• 90712-56-4 5-(4-Bromophenyl)-4,5-dihydroisoxazole 

Downstream Products

• 40620-68-6 3-(p-bromophenyl)-3-hydroxypropionic acid 
• 1374417-01-2 1-(4-bromophenyl)-1-hydroxyhex-5-en-3-one 
• 1374417-23-8 C₁₂H₁₁BrO 
• 65984-66-9 N,N'-Bis-<3-(p-bromphenyl)propyl>-thioharnstoff 
• 65984-53-4 3-(4-Bromophenyl)-1-propanamine 

Relevant articles and documents

NEW TRPA1 ANTAGONISTS

The present invention relates to compounds of Formula (I), to the process for preparing such compounds and to their use in the treatment of a pathological condition or disease susceptible to amelioration by TRPA1 channel inhibition or antagonism.

Isomerization of 3-unsubstituted 4,5-dihydroisoxazoles over alumina. A new synthesis of β-hydroxy nitriles

3-Unsubstituted 4,5-dihydroisoxazoles obtained by nitrosation of arylcyclopropanes are capable of undergoing efficient isomerization into 3-aryl-3-hydroxypropanenitriles during chromatography on alumina.

Formation of carbanions from carboxylate ions bearing electron-withdrawing groups via photoinduced decarboxylation: Addition of generated carbanions to benzaldehyde

The photoinduced decarboxylation of carboxylate ions bearing electron-withdrawing groups using biphenyl and 1,4-dicyanonaphthalene leads to the efficient generation of carbanions under mild conditions. The efficiency of the carbanion generation is strongl