660-49-1

Basic information

• Product Name: 3-FLUORO-5-IODOANILINE
• Synonyms: 3-FLUORO-5-IODOANILINE;3-FLUORO-5-IODO-PHENYLAMINE;5-FLUORO-3-IODOANILINE
• CAS NO: 660-49-1
• Molecular Formula: C₆H₅FIN
• Molecular Weight: 237.01
• Mol File: 660-49-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 279.5 °C at 760 mmHg
• Flash Point: 122.8 °C
• Appearance: /
• Density: 2.008 g/cm³
• Vapor Pressure: 0.004mmHg at 25°C
• Refractive Index: 1.656
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 2.62±0.10(Predicted)
• Sensitive: Light Sensitive
• CAS DataBase Reference: 3-FLUORO-5-IODOANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-FLUORO-5-IODOANILINE(660-49-1)
• EPA Substance Registry System: 3-FLUORO-5-IODOANILINE(660-49-1)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 660-49-1(Hazardous Substances Data)

Usage

General Description

3-Fluoro-5-iodoaniline is a chemical compound with the molecular formula C6H5FINH2. It is an organic building block that contains a fluorine atom and an iodine atom attached to a benzene ring. 3-FLUORO-5-IODOANILINE is used in the synthesis of various pharmaceuticals, agrochemicals, and dyes. It is also utilized as an intermediate in the production of organic compounds and in research laboratories. 3-Fluoro-5-iodoaniline is a potentially hazardous substance and precautions should be taken when handling it, as exposure to this compound can cause skin and eye irritation and may be harmful if swallowed or inhaled. Additionally, it may have adverse effects on aquatic organisms and the environment.

InChI:InChI=1/C6H5FIN/c7-4-1-5(8)3-6(9)2-4/h1-3H,9H2

Upstream product

• 3819-88-3 1-fluoro-3-iodo-5-nitrobenzene 
• 99-65-0 meta-dinitrobenzene 

Downstream Products

• 852807-42-2 1-(3-fluoro-5-iodophenyl)piperazine 
• 1027953-88-3 3-[4-(3-fluoro-5-iodophenyl)piperazin-1-yl]-1-[5-methyl-1-(pyrimidin-2-yl)-1H-pyrazol-4-yl]propan-1-one 
• 710348-26-8 N-(3-fluoro-5-iodophenyl)methanesulfonamide 
• 1369808-80-9 3-fluoro-5-iodo-N,N-dimethylaniline 

Relevant articles and documents

PHENYL-SUBSTITUTED NICOTINIC LIGANDS, AND METHODS OF USE THEREOF

Disclosed are compounds and methods of using them to treat a disorder selected from the group consisting of addiction, pain, obesity, schizophrenia, epilepsy, mania and manic depression, anxiety, Alzheimer's disease, learning deficit, cognition deficit, attention deficit, memory loss, Lewy Body Dementia, Attention Deficit Hyperactivity Disorder (ADHD), Parkinson's disease, Huntington's disease, Tourette's syndrome, amyotrophic lateral sclerosis, inflammation, stroke, spinal cord injury, dyskinesias, obsessive compulsive disorder, chemical substance abuse, alcoholism, memory deficit, pseudodementia, Ganser's syndrome, migraine pain, bulimia, premenstrual syndrome or late luteal phase syndrome, tobacco abuse, post-traumatic syndrome, social phobia, chronic fatigue syndrome, premature ejaculation, erectile difficulty, anorexia nervosa, autism, mutism, trichotillomania, hypothermia, and disorders of sleep.

Synthesis and antitumor activity of novel pyrimidinyl pyrazole derivatives. III. Synthesis and antitumor activity of 3-phenylpiperazinyl-1-trans-propenes

A series of novel 3-[4-phenyl-1-piperazinyl]-1-[5-methyl-1-(2-pyrimidinyl)- 4-pyrazolyl]-1-trans-propenes and related compounds were synthesized and evaluated by their cytotoxic activity against several tumor cell lines in vitro and in vivo antitumor acti

Substituted 5-benzyl-2,4-diaminopyrimidines

The invention relates to substituted 5-benzyl-2,4-diaminopyrimidines of general formula (A) wherein R1is C2-C3 alkyl an R2is heterocyclyl, phenyl or naphthyl, bonded by one of its C-atoms and R3is C2-C6 alkyl, alkenyl, cycloalkyl, cycloalkylalkyl, heterocyclylalkyl, alkylsulfonyl, cycloalkylsulfonyl, cycloalkylalkylsulfamoyl, heterocyclysylfonyl, heterocyclylalkylsulfonyl or dialkylsulfamoyl; wherein alkyl, cycloalkyl and alyenyl can carry up to 6 carbon atoms alone or in compositions and can carry up to 6 ring members heterocyclically, alone, or in compositions and the groups R2and R3can be substituted; and to acid addition salts of compounds. The invention also relates to a method for producing the above 5-benzyl-2,4-diaminopyrimidines, to the intermediate. products that are produced, to corresponding medicaments and to the use of 5-benzyl-2,4-diaminopyrimidines as medicinal preparations. The products have antibiotic properties and are useful for combating or preventing infectious diseases.