66004-20-4Relevant articles and documents
Ring-opening of cyclic ethers with carbon-carbon bond formation by Grignard reagents
Christensen, Stig Holden,Holm, Torkil,Madsen, Robert
, p. 4942 - 4946 (2014/07/07)
The ring-opening of cyclic ethers with concomitant C-C bond formation was studied with a number of Grignard reagents. The transformation was performed in a sealed vial by heating to ～160 °C in an aluminum block or at 180 °C in a microwave oven. Good yields of the product alcohols were obtained with allyl- and benzylmagnesium halides when the ether was tetrahydrofuran or 3,3-dimethyloxetane. Lower yields were obtained with substituted tetrahydrofurans while no ring-opening was observed with tetrahydropyran. Only highly reactive allyl and benzyl Grignard reagents participated in the transformation while no reaction occurred with other alkylmagnesium halides.
Enantioselective intramolecular friedel-crafts-type α-arylation ofaldehydes
Nicolaou, K. C.,Reingruber, Ruediger,Sarlah, David,Braese, Stefan
supporting information; experimental part, p. 2086 - 2087 (2009/07/30)
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Synthesis and stereochemical studies: Chemical and catalytic reductions of a new class of dihydropyrrole and tetrahydropyridine derivatives
Ghosh, Arindam,Bhattacharya, Sudin,Raychaudhuri, S. R.,Chatterjee, Amreshwar
, p. 299 - 309 (2007/10/02)
Tetrahydropyridine derivatives 1g,h on catalytic (PtO2/H2) or hydride (LAH or NaBH4) reductions afford stereoselectively the corresponding cis-amines 20a,b.Catalytic reduction of the dihydropyrrole derivative 1e gives a complex material; while NaBH4 reduc
