660431-65-2 Usage
General Description
[1-(2-Fluorophenyl)-1-tosyl]methyl isocyanide is a chemical compound with the molecular formula C16H14FNO2S and a molecular weight of 305.35 g/mol. It is a tosylated isocyanide derivative with a fluorophenyl group attached to the carbon atom. [1-(2-FLUOROPHENYL)-1-TOSYL]METHYL ISOCYANIDE is commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals and bioactive compounds. It is known for its reactivity as a nucleophile and as a ligand in transition metal-catalyzed reactions. Due to its versatile applications in chemical research, [1-(2-Fluorophenyl)-1-tosyl]methyl isocyanide is a valuable and widely used compound in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 660431-65-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,0,4,3 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 660431-65:
(8*6)+(7*6)+(6*0)+(5*4)+(4*3)+(3*1)+(2*6)+(1*5)=142
142 % 10 = 2
So 660431-65-2 is a valid CAS Registry Number.
InChI:InChI=1/C15H12FNO2S/c1-11-7-9-12(10-8-11)20(18,19)15(17-2)13-5-3-4-6-14(13)16/h3-10,15H,1H3
660431-65-2Relevant articles and documents
In silico-driven multicomponent synthesis of 4,5- and 1,5-disubstituted imidazoles as indoleamine 2,3-dioxygenase inhibitors
Fallarini,Massarotti,Gesù,Giovarruscio,Coda Zabetta,Bergo,Giannelli,Brunco,Lombardi,Sorba,Pirali
, p. 409 - 419 (2016/04/01)
Indoleamine 2,3-dioxygenase is involved in pathological immune escape and has recently become an attractive target for anti-cancer therapy. 4-Phenylimidazole (4-PI) provides a promising starting point for the development of IDO1 inhibitors. With the aim o