6607-92-7

Basic information

• Product Name: 3-(2-hydroxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one
• CAS NO: 6607-92-7
• Molecular Formula: C₁₆H₁₄O₃
• Molecular Weight: 254.2806
• Mol File: 6607-92-7.mol
• Article Data: 44

Chemical Properties

• Boiling Point: 444.7°C at 760 mmHg
• Flash Point: 167.3°C
• Density: 1.197g/cm³
• Vapor Pressure: 1.6E-08mmHg at 25°C
• Refractive Index: 1.631
• CAS DataBase Reference: 3-(2-hydroxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-hydroxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one(6607-92-7)
• EPA Substance Registry System: 3-(2-hydroxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one(6607-92-7)

Safety Data

• Hazardous Substances Data: 6607-92-7(Hazardous Substances Data)

Upstream product

• 24531-81-5 4'-methoxyflavylium ion 
• 99618-46-9 (Z)-3-(2-Hydroxy-phenyl)-1-(4-methoxy-phenyl)-propenone 
• 89-95-2 2-methyl-benzyl alcohol 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 1310-58-3 potassium hydroxide 
• 123-11-5 4-methoxy-benzaldehyde 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 533-58-4 2-Iodophenol 
• 1178871-13-0 (E)-1-[diethoxy(methyl)silyl]-2-[dimethyl(phenyl)silyl]ethylene 
• 794-94-5 p-Methoxybenzoic anhydride 
• 90-02-8 salicylaldehyde 
• 1777-55-5 (4-methoxyphenacylidene)triphenyl phosphorane 
• 201049-10-7 (E)-3-(2-(methoxymethoxy)phenyl)-1-(4-methoxyphenyl)prop-2-en-1-one 
• 5533-04-0 2-(methoxymethoxy)benzaldehyde 

Downstream Products

• 24531-81-5 4'-methoxyflavylium ion 
• 99618-46-9 (Z)-3-(2-Hydroxy-phenyl)-1-(4-methoxy-phenyl)-propenone 
• 132629-78-8 (E)-3-(2-(allyloxy)phenyl)-1-(4-methoxyphenyl)prop-2-en-1-one 
• 32816-75-4 (5-bromobenzofuran-2-yl)(4-methoxyphenyl)methanone 
• 132629-88-0 (4aS,10aS)-3-(4-Methoxy-phenyl)-10,10a-dihydro-1H,4aH-9-oxa-2-thia-phenanthrene 
• 132629-88-0 (4aS,10aR)-3-(4-Methoxy-phenyl)-10,10a-dihydro-1H,4aH-9-oxa-2-thia-phenanthrene 
• 5594-98-9 2-(4-methoxy-phenyl)-chroman 
• 1374022-09-9 1-furan-2-yl-2-[2-(4-methoxyphenyl)chromen-4-ylidene]ethanone 
• 1374022-10-2 C₂₅H₂₀O₃ 
• 1414854-03-7 3-(2-(4-methoxyphenyl)-4H-chromen-4-yl)-1H-indole 

Relevant articles and documents

Electronic effect control of regioselectivity in the Michael-Addition inspired cascade reaction of 1,3-dimethyl-6-amino-uracil and 2-hydroxychalcones

An unexpected Brosnted acid-catalyzed cascade reaction of 1,3-dimethyl-6-aminouracil with 2-hydroxychalcone has been developed to afford pyrido[2,3–d]pyrimidine-2,4-diones derivatives and 2,8-dioxabicyclo[3.3.1]nonane derivatives in moderate to good yield

Development of pyrazoline-based derivatives as aminopeptidase N inhibitors to overcome cancer invasion and metastasis

Aminopeptidase N is considered as a promising anti-tumor target due to its role in tumor invasion, metastasis and angiogenesis. In this report, a new series of pyrazoline-based derivatives were designed, synthesized and evaluated for biological activities

Palladium-Catalyzed Cascade Reactions of 2-(Cyanomethoxy)chalcones with Arylboronic Acids: Selective Synthesis of Emissive Benzofuro[2,3- c]pyridines

The Pd(II)-catalyzed cascade reactions of 2-(cyanomethoxy)chalcones with arylboronic acids were demonstrated, allowing the rapid construction of benzofuro[2,3-c]pyridine skeletons with excellent selectivity. These transformations involve the domino-style formation of C-C/C-C/C-N bonds through nitrile carbopalladation, intramolecular Michael addition, cyclization, and aromatization. This chemistry allows for the reactions of 2-(cyanomethoxy)chalcones with thiophen-3-ylboronic acid, providing 3-aryl-1-(thiophen-3-yl)benzofuro[2,3-c]pyridines in moderate to good yields. In addition, the resulting products represent a new class of emissive fluorophores.