660853-73-6

Basic information

• Product Name: [(S)-1-Benzyl-3-cyano-2-oxo-3-(triphenyl-λ⁵-phosphanylidene)-propyl]-carbamic acid 1-isopropyl-2-methyl-propyl ester
• Synonyms: [(S)-1-Benzyl-3-cyano-2-oxo-3-(triphenyl-λ⁵-phosphanylidene)-propyl]-carbamic acid 1-isopropyl-2-methyl-propyl ester
• CAS NO: 660853-73-6
• Molecular Weight: 590.702
• Mol File: 660853-73-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [(S)-1-Benzyl-3-cyano-2-oxo-3-(triphenyl-λ⁵-phosphanylidene)-propyl]-carbamic acid 1-isopropyl-2-methyl-propyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(S)-1-Benzyl-3-cyano-2-oxo-3-(triphenyl-λ⁵-phosphanylidene)-propyl]-carbamic acid 1-isopropyl-2-methyl-propyl ester(660853-73-6)
• EPA Substance Registry System: [(S)-1-Benzyl-3-cyano-2-oxo-3-(triphenyl-λ⁵-phosphanylidene)-propyl]-carbamic acid 1-isopropyl-2-methyl-propyl ester(660853-73-6)

Safety Data

• Hazardous Substances Data: 660853-73-6(Hazardous Substances Data)

Upstream product

• 81861-04-3 (S)-2-(1-Isopropyl-2-methyl-propoxycarbonylamino)-3-phenyl-propionic acid 
• 16640-68-9 cyanomethylene triphenylphosphorane 
• 660853-81-6 (S)-2-(1-Isopropyl-2-methyl-propoxycarbonylamino)-3-phenyl-propionic acid methyl ester 
• 30250-57-8 2,4-dimethyl-3-pentyl chloroformate 
• 600-36-2 2,4-dimethyl-3-pentanol 

Relevant articles and documents

Design of Potent, Selective, and Orally Bioavailable Inhibitors of Cysteine Protease Cathepsin K

Osteoclast-mediated bone matrix resorption has been attributed to cathepsin K, a cysteine protease of the papain family that is abundantly and selectively expressed in osteoclast. Inhibition of cathepsin K could potentially be an effective method to preve