660866-51-3Relevant articles and documents
Application of ynamides in the synthesis of 2-amidoindoles
Dooleweerdt, Karin,Ruhland, Thomas,Skrydstrup, Troels
supporting information; experimental part, p. 221 - 224 (2009/06/20)
A Pd-catalyzed, one-pot, two-step synthesis of 2-amidoindoles from ynamides and o-iodoanilines is reported. A key highlight of this sequence is that after the Sonogashira reaction, intramolecular cyclization to the indole occurs spontaneously without acti