66107-32-2

Basic information

• Product Name: 4-Cyanophenyl trifluoromethanesulfonate
• Synonyms: 4-Cyanophenyl trifluoromethanesulfonate
• CAS NO: 66107-32-2
• Molecular Formula: C₈H₄F₃NO₃S
• Molecular Weight: 251.18
• Mol File: 66107-32-2.mol
• Article Data: 31

Chemical Properties

• Boiling Point: 317.0±42.0 °C(Predicted)
• Appearance: /
• Density: 1.58±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 4-Cyanophenyl trifluoromethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Cyanophenyl trifluoromethanesulfonate(66107-32-2)
• EPA Substance Registry System: 4-Cyanophenyl trifluoromethanesulfonate(66107-32-2)

Safety Data

• Hazardous Substances Data: 66107-32-2(Hazardous Substances Data)

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 767-00-0 4-cyanophenol 
• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 
• 557-21-1 zinc(II) cyanide 
• 66107-30-0 4-bromophenyl trifluoromethanesulfonate 
• 17763-67-6 Phenyl triflate 
• 138373-10-1 4-cyanophenyl mesylate 
• 421-83-0 trifluoromethane sulfonyl chloride 
• 1493-13-6 trifluorormethanesulfonic acid 

Downstream Products

• 10282-31-2 4-morpholinobenzonitrile 
• 131516-07-9 (S)-4-(2,3-Dihydro-furan-2-yl)-benzonitrile 
• 131516-07-9 (R)-2-(4-cyanophenyl)-2,3-dihydrofuran 
• 131516-14-8 (R)-4-(2,5-Dihydro-furan-2-yl)-benzonitrile 
• 131516-14-8 (S)-4-(2,5-Dihydro-furan-2-yl)-benzonitrile 
• 1443-80-7 4-cyanophenyl methyl ketone 
• 127087-67-6 (Z)-1-Butoxy-2-(4-cyanophenyl)ethylene 
• 127087-66-5 (E)-1-Butoxy-2-(4-cyanophenyl)ethylene 
• 453537-17-2 4-(1-butoxyvinyl)benzonitrile 
• 154318-66-8 4-[1-(2-Dimethylamino-ethoxy)-vinyl]-benzonitrile 
• 141172-00-1 N-methyl-N-<1-(4-cyanophenyl)ethenyl>acetamide 
• 97780-99-9 ((E)-4-But-2-enyl)-benzonitrile 
• 90433-29-7 4-(3-methylbut-2-en-1-yl)benzonitrile 
• 623-26-7 terephthalonitrile 

Relevant articles and documents

Ni-Catalyzed Cross-Electrophile Coupling of Aryl Triflates with Thiocarbonates via C-O/C-O Bond Cleavage

A nickel-catalyzed reductive coupling of aryl triflates with thiocarbonates is reported here. Both electron-rich and -deficient aryl C(sp2)-O electrophiles as well as a class of O-tBu S-alkyl thiocarbonates are compatible with the optimized reaction conditions, as evidenced by 49 examples. The reaction also proceeds with good chemoselective cleavage of the C-O bond with regard to thioesters. This work broadens the scope of nickel-catalyzed reductive cross-electrophile coupling reactions.

Base-promoted selective O-phosphorylation of aryl triflates with P(O)-H compounds

Compared to previous transition metal-catalyzed C-phosphorylation reactions for constructing C–P bonds, in the absence of transition metal catalysts and ligands, a direct O-phosphorylation of aryl triflates selectively occurred with P(O)-H compounds in the presence of a base via the construction of O–P bonds. This transformation proceeds under simple and mild conditions, and provides a new method for the preparation of valuable organophosphoryl compounds from readily available P(O)-H compounds and triflates.

Practical Ni-Catalyzed Cross-Coupling of Unsaturated Zinc Pivalates with Unsaturated Nonaflates and Triflates

A practical nickel-catalyzed cross-coupling of (hetero)aryl or alkynylzinc pivalates with various unsaturated nonaflates or triflates is described. Organozinc pivalates allow these cross-couplings to take place with high yields and a low catalyst loading (0.5 mol %). Couplings with (E)- and (Z)-alkenyl triflates proceed with retention of configuration.