6622-54-4

Basic information

• Product Name: 9-CARBAZOLEPROPIONIC ACID
• Synonyms: 3-(9-Carbazolyl)propionic acid, 9-(2-Carboxyethyl)carbazole;9H-Carbazole-9-propanoic acid
• CAS NO: 6622-54-4
• Molecular Formula: C₁₅H₁₃NO₂
• Molecular Weight: 239.27
• Mol File: 6622-54-4.mol
• Article Data: 8

Chemical Properties

• Melting Point: 172-176 °C
• Boiling Point: 403.3°C at 760 mmHg
• Flash Point: 197.7°C
• Appearance: /
• Density: 1.23g/cm³
• Vapor Pressure: 3.15E-07mmHg at 25°C
• Refractive Index: 1.637
• CAS DataBase Reference: 9-CARBAZOLEPROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 9-CARBAZOLEPROPIONIC ACID(6622-54-4)
• EPA Substance Registry System: 9-CARBAZOLEPROPIONIC ACID(6622-54-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 6622-54-4(Hazardous Substances Data)

Usage

Uses

3-(9H-Carbazol-9-yl)propanoic Acid can be used as potential inhibitors for Human Farnesyltransferase.

InChI:InChI=1/C15H13NO2/c17-15(18)9-10-16-13-7-3-1-5-11(13)12-6-2-4-8-14(12)16/h1-8H,9-10H2,(H,17,18)

Upstream product

• 5337-01-9 N-(2-cyanoethyl)carbazole 
• 539-74-2 Ethyl 3-bromopropionate 
• 86-74-8 9H-carbazole 
• 590-92-1 3-Bromopropionic acid 
• 3395-91-3 Methyl 3-bromopropionate 

Downstream Products

• 10257-99-5 5,6-dihydro-pyrido[3,2,1-jk]carbazol-4-one 
• 116605-12-0 5-benzyl-pyrido[3,2,1-jk]carbazol-4-one 

Relevant articles and documents

Electrochemical Polymerization Provides a Function-Integrated System for Water Oxidation

Water oxidation is a key reaction in natural and artificial photosynthesis. In nature, the reaction is efficiently catalyzed by a metal-complex-based catalyst surrounded by hole-transporting amino acid residues. However, in artificial systems, there is no example of a water oxidation system that has a catalytic center surrounded by hole transporters. Herein, we present a facile strategy to integrate catalytic centers and hole transporters in one system. Electrochemical polymerization of a metal-complex-based precursor afforded a polymer-based material (Poly-1). Poly-1 exhibited excellent hole-transporting ability and catalyzed water oxidation with high performance. It was also revealed that the catalytic activity was almost completely suppressed in the absence of the hole-transporting moieties. The present study provides a novel strategy for constructing efficient molecule-based systems for water oxidation.

Thermally Activated Delayed Fluorescence Benzyl Cellulose Derivatives for Nondoped Organic Light-Emitting Diodes

Thermally activated delayed fluorescence (TADF) benzyl cellulose derivatives (TBC-X), which contained both carbazole (host) and phthalimide-based TADF dye (guest) moieties, were prepared from 2,3-di-O-benzyl cellulose in high yields. The TBC-X samples were soluble in common organic solvents such as CH2Cl2, CHCl3, THF, and toluene. The photoluminescence spectra of TBC-X spin-coated films had a single emission peak derived only from guest moieties, which indicated efficient energy transfer from the host to guest moieties. The TBC-10 (with a content of host and guest moieties of 93 and 7, respectively) in a spin-coated film had the highest photoluminescence quantum yield of 55.3% and TADF characteristics. A nondoped organic light-emitting diode with TBC-10 as the emitting layer showed green emission (λEL = 517 nm) and achieved a maximum external quantum efficiency of 5.9%.

Peptide chemistry applied to a new family of phenothiazine-containing inhibitors of human farnesyltransferase

Novel phenothiazine derivatives bearing an amino acid residue were synthesized via peptide chemistry, and evaluated for their inhibitory potential on human farnesyltransferase. The phenothiazine unit proved to be an important bulky unit in the structure o