66335-37-3 Usage
Description
5'-Deoxy-5-fluoro-2',3'-O-isopropylidene-D-cytidine is a chemical compound that is classified as a nucleoside analog. It is a derivative of the nucleoside cytidine, with a fluorine atom replacing the hydroxyl group at the 5' position and an isopropylidene group protecting the 2' and 3' hydroxyl groups. This modification enhances its stability and bioavailability, making it a valuable compound for various applications in the field of organic synthesis.
Uses
Used in Organic Synthesis:
5'-Deoxy-5-fluoro-2',3'-O-isopropylidene-D-cytidine is used as an intermediate in the synthesis of various biologically active compounds. Its unique structure allows for the development of new molecules with potential applications in the pharmaceutical and chemical industries.
Used in Pharmaceutical Research:
As a nucleoside analog, 5'-Deoxy-5-fluoro-2',3'-O-isopropylidene-D-cytidine may have potential applications in the development of antiviral, anticancer, and immunosuppressive drugs. Its ability to interact with cellular machinery and disrupt nucleic acid synthesis could make it a promising candidate for therapeutic intervention in various diseases.
Used in Chemical Research:
5'-Deoxy-5-fluoro-2',3'-O-isopropylidene-D-cytidine's unique structure and properties make it a valuable tool for studying the interactions between nucleosides and other biomolecules. It can be used to investigate the mechanisms of nucleic acid synthesis, replication, and repair, as well as to develop new methods for the detection and quantification of nucleosides in biological samples.
Check Digit Verification of cas no
The CAS Registry Mumber 66335-37-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,3,3 and 5 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 66335-37:
(7*6)+(6*6)+(5*3)+(4*3)+(3*5)+(2*3)+(1*7)=133
133 % 10 = 3
So 66335-37-3 is a valid CAS Registry Number.
66335-37-3Relevant articles and documents
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Cook,A.F. et al.
, p. 1330 - 1335 (1979)
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5'-Deoxy-5-fluoropyrimidine nucleosides
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, (2008/06/13)
Novel 5'-deoxy-5-fluoropyrimidine nucleosides are potent anti-tumor agents. Preferred compounds are 5'-deoxy-5-fluorocytidine and 5'-deoxy-5-fluorouridine.
