66343-88-2Relevant articles and documents
Intramolecular Kinetic Deuterium Isotope Effects on Microsomal Hydroxylation and Chemical Chlorination of Toluene-α-d1 and Toluene-α,α-d2
Hanzlik, Robert P.,Hogberg, Kerstin,Moon, Joseph B.,Judson, Charles M.
, p. 7164 - 7167 (1985)
Deuterated toluenes PhCH2D and PhCHD2 were synthesized and subjected separately to microsomal hydroxylation in vitro.Mass spectral analysis of the resulting benzyl alcohols indicated substatial excess retention of deuterium, a consequence of the combined
Controlling Selectivity in the Synthesis of Z-α,β-Unsaturated Amidines by Tuning the N-Sulfonyl Group in a Rhodium(II) Catalyzed 1,2-H Shift
Boyer, Alistair,Martin, Matthew L.
, p. 5857 - 5861 (2021/11/27)
N2-Sulfonyl-α-diazo amidines can be synthesized by the reaction of electron rich alkynyl amines with electron poor sulfonyl azides through 1,3-dipolar cycloaddition that proceeds with perfect regioselectivity. In the presence of rhodium(II) carboxylate catalysts, denitrogenation occurs to give the corresponding metallocarbene but there are then two competing processes: 1,2–H shift and O-transfer from the sulfonyl group to the metallocarbene center. The outcome can be controlled using an electron poor nitrobenzenesulfonyl group and large carboxylate rhodium ligands to select for 1,2–H shift, forming α,β-unsaturated amidines in high yield and with excellent Z-selectivity.
Mechanistic aspects of the reaction of anionic iron(0)-olefin complexes with organic halides. detection and characterization of paramagnetic organometallic intermediates
Hill, Dale H.,Parvez, Masood A.,Sen, Ayusman
, p. 2889 - 2901 (2007/10/02)
The scope and the mechanism of the reactions of [CpFe(COD)][Li(TMEDA) (Cp = C5H5-; COD = 1,5-cyclooctadiene; TMEDA = Me2NCH2CH2NMe2), 1, with a number of organic monohalides and geminal dih
