66361-73-7

Basic information

• Product Name: m-methoxybenzyloxynaphthalenone
• Synonyms: m-methoxybenzyloxynaphthalenone
• CAS NO: 66361-73-7
• Molecular Weight: 282.339
• Mol File: 66361-73-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: m-methoxybenzyloxynaphthalenone(CAS DataBase Reference)
• NIST Chemistry Reference: m-methoxybenzyloxynaphthalenone(66361-73-7)
• EPA Substance Registry System: m-methoxybenzyloxynaphthalenone(66361-73-7)

Safety Data

• Hazardous Substances Data: 66361-73-7(Hazardous Substances Data)

Upstream product

• 3470-50-6 6-Hydroxy-1-tetralone 
• 824-98-6 m-methoxybenzyl chloride 

Downstream Products

• 66361-74-8 6-(3-Methoxy-benzyloxy)-3,4-dihydro-2H-naphthalen-1-one oxime 
• 66362-05-8 C₂₅H₂₅NO₅S 

Relevant articles and documents

Synthesis of 2-(N-substituted amino)-6-hydroxy-1,2,3,4-tetrahydronaphthalen-1-ol derivatives

trans-6-Hydroxy-2-(1-methyl-3-phenylpropyl)amino-1,2,3,4-tetrahydronaphth alen-1-ol (8a), trans-6-hydroxy-2-(1-methyl-2-phenoxyethyl)amino-1,2,3,4-tetrahydronaphtha len-1-ol (8b) and trans-1,6-dihydroxy-2-(1-methyl-3-phenylpropyl)amino-1,2,3,4-tetrahydronap hthalene-5-carboxamide (9a) were synthesized as a part of our search for useful cardiovascular agents. 2-(N-Substituted amino)-6-alkoxy-1,2,3,4-tetrahydronaphthalen-1-ols (10-31) having various substituents at the 5-, 6- and 7-positions of the naphthalene ring were prepared by a five-step sequence of reactions starting from 3,4-dihydro-1(2H)-naphthalenone derivatives (36). Furthermore 2-(N-substituted amino)-1-indanol derivatives (33) and 6-(N-substituted amino)-2-hydroxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ols (34, 35) were obtained by the reductive alkylation of the corresponding amino alcohols with carbonyl compounds. These N-substituted amino alcohols (8-35) were tested for vasodilating activity in anesthetized dogs and for β-blocking activity using isolated guinea pig atrial preparations.