66366-98-1

Basic information

• Product Name: 2(1H)-Quinoxalinone,3-ethyl-3,4-dihydro-(9CI)
• Synonyms: 2(1H)-Quinoxalinone,3-ethyl-3,4-dihydro-(9CI);3-ETHYL-3,4-DIHYDROQUINOXALIN-2(1H)-ONE;3-ethyl-3,4-dihydro-1H-quinoxalin-2-one
• CAS NO: 66366-98-1
• Molecular Formula: C₁₀H₁₂N₂O
• Molecular Weight: 176.22
• Product Categories: PIPERIDINE
• Mol File: 66366-98-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 367.6±31.0 °C(Predicted)
• Appearance: /
• Density: 1.085±0.06 g/cm3(Predicted)
• PKA: 13.28±0.40(Predicted)
• CAS DataBase Reference: 2(1H)-Quinoxalinone,3-ethyl-3,4-dihydro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Quinoxalinone,3-ethyl-3,4-dihydro-(9CI)(66366-98-1)
• EPA Substance Registry System: 2(1H)-Quinoxalinone,3-ethyl-3,4-dihydro-(9CI)(66366-98-1)

Safety Data

• Hazardous Substances Data: 66366-98-1(Hazardous Substances Data)

Usage

Structure

Derivative of quinoxalinone with an ethyl group and a dihydro structure at the 3 and 4 positions

Potential applications

Organic synthesis, pharmaceuticals (as a building block for the synthesis of other organic compounds or as a precursor for the development of new drugs or materials)

Need for further research

To fully understand the properties and potential uses of the compound.

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 533-68-6 2-bromobutyric acid ethyl ester 
• 13297-35-3 3-ethyl-3,4-dihydroquinoxalin-2(1H)-one 
• 15933-07-0 Ethyl 2-oxobutanoate 

Downstream Products

• 66367-01-9 3-ethyl-6-phenyl-1H,6H-pyrrolo[1,2,3-de]quinoxaline-2,5-dione 

Relevant articles and documents

Rhodium-catalyzed transfer hydrogenation of quinoxalines with water as a hydrogen source

Rhodium-catalyzed transfer hydrogenation of quinoxalines with water as a hydrogen source was reported. The reaction allowed the simple preparation of tetrahydroquinoxalines under mild conditions. The deuterium-labelling experiment confirmed that water is

Versatile (Pentamethylcyclopentadienyl)rhodium-2,2′-Bipyridine (Cp?Rh-bpy) Catalyst for Transfer Hydrogenation of N-Heterocycles in Water

An investigation employing the catalytic system consisting of (pentamethylcyclopentadienyl)rhodium dichloride dimer [Cp?RhCl2]2 and 2,2′-bipyridine (bpy) for transfer hydrogenation of a variety of quinoxalines, quinoxalinones, quinolines and indoles under aqueous conditions with formate as the hydrogen source is reported. This approach provides various tetrahydroquinoxalines, dihydroquinoxalinones, tetrahydroquinolines and indolines in good to excellent yields. The activity of the catalyst towards quinoxalines and quinoxalinones is excellent, with a substrate to catalyst ratio (S/C) of 10000 being feasible. The choice of ligand is critical to the catalysis, and the aqueous phase reduction is shown to be highly pH-dependent, with acidic pH values needed for optimal reduction. The catalyst is easy to access, and the reaction is operationally simple without requiring an inert atmosphere.