663910-97-2Relevant articles and documents
Models for biological trinuclear copper clusters. Characterization and enantioselective catalytic oxidation of catechols by the copper(II) complexes of a chiral ligand derived from (S)-(-)-1,1'-binaphthyl-2,2'-diamine.
Mimmi, Maria Chiara,Gullotti, Michele,Santagostini, Laura,Battaini, Giuseppe,Monzani, Enrico,Pagliarin, Roberto,Zoppellaro, Giorgio,Casella, Luigi
, p. 2192 - 2201 (2004)
The dinuclear and trinuclear Cu(II) complexes of an octadentate ligand derived from (S)-1,1'-binaphthyl-2,2'-diamine have been prepared and characterized by UV/Vis, CD, EPR and NMR spectroscopy. The ligand contains two tridentate aminobis(benzimidazole) d
Tyrosinase inactivation in its action on dopa
Mu?oz-Mu?oz,Acosta-Motos,Garcia-Molina,Varon,Garcia-Ruíz,Tudela,Garcia-Cánovas,Rodríguez-López
experimental part, p. 1467 - 1475 (2011/12/01)
Under aerobic or anaerobic conditions, tyrosinase undergoes a process of irreversible inactivation induced by its physiological substrate l-dopa. Under aerobic conditions, this inactivation occurs through a process of suicide inactivation involving the fo
Metallo-ROS in Alzheimer's disease: Oxidation of neurotransmitters by CuII-β-amyloid and neuropathology of the disease
Da Silva, Giordano F. Z.,Ming, Li-June
, p. 3337 - 3341 (2008/03/12)
A clear mind: The CuII-β-amyloid (Aβ) complex has been shown to exhibit enzyme-like metal-centered oxidative and hydroxylation catalyses. Metal-centered oxidation of various neurotransmitters by CuAβ under biomimetic conditions has verified the bio-relevance of the metal-centered catalyses and is expected to provide a chemical basis for the better understanding of the etiology of Alzheimer's disease. ROS = reactive oxygen species. (Figure Presented).
