66408-27-3

Basic information

• Product Name: 13-Hydroxyoxyberberine
• Synonyms: 13-Hydroxyoxyberberine;13-Hydroxy-8-oxoberberine;5,6-Dihydro-13-hydroxy-9,10-dimethoxy-8H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-8-one
• CAS NO: 66408-27-3
• Molecular Formula: C20H17NO6
• Molecular Weight: 367.35208
• Mol File: 66408-27-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 13-Hydroxyoxyberberine(CAS DataBase Reference)
• NIST Chemistry Reference: 13-Hydroxyoxyberberine(66408-27-3)
• EPA Substance Registry System: 13-Hydroxyoxyberberine(66408-27-3)

Safety Data

• Hazardous Substances Data: 66408-27-3(Hazardous Substances Data)

Usage

Description

13-Hydroxyoxyberberine is a natural alkaloid compound derived from several plant species, particularly the Berberis genus. It is formed through the oxidation of oxyberberine and is characterized by the presence of a hydroxyl group at the 13th position of the molecule. 13-Hydroxyoxyberberine has garnered attention for its potential pharmacological properties, such as anti-inflammatory, anti-diabetic, and anticancer activities. As a natural alternative to synthetic drugs, 13-Hydroxyoxyberberine holds promise for the treatment of various diseases and continues to be a subject of research for its unique chemical structure and potential health benefits.

Uses

Used in Pharmaceutical Industry:
13-Hydroxyoxyberberine is used as a potential therapeutic agent for various diseases due to its pharmacological effects. Its anti-inflammatory properties make it a candidate for treating inflammatory conditions, while its anti-diabetic effects suggest potential use in managing blood sugar levels in diabetes treatment.
Used in Anticancer Applications:
In the field of oncology, 13-Hydroxyoxyberberine is utilized as an anticancer agent, targeting the inhibition and prevention of tumor growth. Its potential to disrupt cancer cell proliferation and induce apoptosis positions it as a valuable compound in the development of novel cancer therapies.
Used in Drug Development:
13-Hydroxyoxyberberine's unique chemical structure and natural origin make it an attractive candidate for drug development. Researchers are exploring its potential to be formulated into new drugs or combined with existing treatments to enhance their efficacy and provide natural alternatives to synthetic medications.
Overall, 13-Hydroxyoxyberberine's diverse range of potential applications across the pharmaceutical industry highlights its significance as a compound worthy of further study and development.

Upstream product

• 61138-60-1 8-methoxyberberine phenolbetaine 
• 71733-96-5 9,10,13a-trimethoxy-2,3-(methylenedioxy)-8,13-dioxo-5,6,13,13a-tetrahydro-8H-dibenzoquinolizine 
• 67-56-1 methanol 
• 2086-83-1 berberine 
• 29074-38-2 canadine 
• 71766-69-3 13a-hydroxy-9,10-dimethoxy-2,3-(methylenedioxy)-8,13-dioxo-5,6,13,13a-tetrahydro-8H-dibenzoquinolizine 

Downstream Products

• 71700-15-7 12b-hydroxy-9,10-dimethoxy-5H-[1,3]dioxolo[4'',5'':4',5']benzo[1',2':4,5]azepino[2,1-a]isoindole-8,13(6H,12bH)-dione 

Relevant articles and documents

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Berberis ALKALOIDS. XVI. STRUCTURE OF BERPODINE

The alkaloid composition of young shoots of Berberis heteropoda has been studied.Together with known alkaloids, we have isolated the new dimeric base berpodine and have established its structure by a study of spectral characteristics and by chemical transformations.The known alkaloid isotetrandrine has also been isolated from this plant, for the first time.